DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B2

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_172767.1	Gene:	CYP71B2 / 837865	AraportID:	AT1G13080	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	135/500 - (27%)
Similarity:	231/500 - (46%)	Gaps:	61/500 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLMVFLGLLALVTLLQ--WLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            :|:.|. |::|:|::.  :|.:|......|||.|..||:||.|..:....|..|.:|:.:||.|.
plant     3 ILLCFF-LVSLLTIVSSIFLKQNKTSKFNLPPSPSSLPIIGNLHHLAGLPHRCFHKLSIKYGPLV 66

  Fly    89 STRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTLNGYGIINST----GKLWKDQRR-- 145
            ..||||...||:|..:......:..  |...||.|.....|: ||..:.|    |:.|::.|:
plant    67 FLRLGSVPVVVISSSEAAEAVLKTNDLECCSRPKTVGSGKLS-YGFKDITFAPYGEYWREVRKLA 130

  Fly   146 ----FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSL 206
                |...|::.|  .|:   :::....::.:|.|     .|....|||:|.......:::||.:
plant   131 VIELFSSKKVQSF--RYI---REEEVDFVVKKVSE-----SALKQSPVDLSKTFFSLTASIICRV 185

  Fly   207 MMSTRFS-----IDDPKFRRFNFLIEEGMRLFGEIHTVDYIP---------TMQCFPSISTAKNK 257
            .:...|:     ||..   |...|:.|.....|.....|:.|         ..|....|    ||
plant   186 ALGQNFNESGFVIDQD---RIEELVTESAEALGTFTFSDFFPGGLGRFVDWLFQRHKKI----NK 243

  Fly   258 IAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVI 322
            :.:   |:..|||.|||||.:.....| :|:|...|..|:|.:    |::.|  |.:.:.|..::
plant   244 VFK---ELDAFYQHVIDDHLKPEGRKN-QDIVTLILDMIDKQE----DSDSF--KLNMDNLKAIV 298

  Fly   323 IDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVG--RHRLPTIEDLQYLPITESTILE 385
            :|:|.||::|...|::|....::|||:.|::.|:.:...:|  :.|: |.|||..:......:.|
plant   299 MDVFLAGIDTSAVTMIWAMTELIRNPRVMKKAQESIRTTLGLKKERI-TEEDLGKVEYLNHILKE 362

  Fly   386 SMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKV 450
            :.|....:|..........:::.||.||..:.:...:.::..||..|..||||.|.||.::....
plant   363 TFRLHPALPFVVPRETMSHIKIQGYDIPPKTQIQLNVWTIGRDPKRWNDPEEFNPERFANSSVDF 427

  Fly   451 RKPEY-FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG 494
            |...: .:|||.|||:|.|..:|...:.|...:.::.||.::|:|
plant   428 RGQHFDLLPFGSGRRICPGMPMAIASVELALMNLLYYFDWSMPDG 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	126/469 (27%)
CYP71B2	NP_172767.1	p450	5..500	CDD:386267	133/497 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000