DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B13

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_197896.1	Gene:	CYP71B13 / 832585	AraportID:	AT5G25140	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	132/524 - (25%)
Similarity:	243/524 - (46%)	Gaps:	68/524 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HLLMVFLGLLALVTLLQWLVRNYRELRK-LPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            ::::||:...::     ::.:|.|:.:| |||||..||:||.|..:||:.|....:|:::||.|.
plant     5 YIIVVFVFFASI-----FIAKNTRKTKKNLPPGPPRLPIIGNLHQLGSKPHRSMFKLSEKYGPLV 64

  Fly    89 STRLGSQLTVVMSDYKMI--------RECFRREEFT-------GRPDTPFMQTLNGYGIINSTGK 138
            ..:||...:||.|..:.:        ::|..|...|       ...|..|.          ...|
plant    65 YLKLGKVPSVVASTPETVKDVLKTFDKDCCSRAFLTYPARISYNLKDLAFA----------PYSK 119

  Fly   139 LWKDQRR------FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISV 197
            .||..|:      :...:::.|         :.:::..:....|||.| .||..:.|:::..:..
plant   120 YWKAVRKMTVVELYTAKRVKSF---------RNIREEEVASFVEFIKH-SASLEEIVNLNQTLVK 174

  Fly   198 AVSNVICSLMMSTRFSIDDPKFRR-FNFLIEEGMRLFGEIHTVDYIPTM-QCFPSISTAKNKIAQ 260
            ...:|||.:...  .:::..|... :..:|...|.:.|.....||.|.: .....|:...||..:
plant   175 LSGSVICRVGFG--INLEGSKLENTYEEVIHGTMEVLGSFAASDYFPVIGGIIDRITGLHNKCEK 237

  Fly   261 NRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDL 325
            .......|:...|..|..  |..:..|:||. |.::|:.:. |.....|. :||.:   .:::|:
plant   238 VFKGTDSFFDHCIKHHLE--DGGSKDDIVDL-LLKVERGEI-GLGEFQFT-RNHTK---GILLDI 294

  Fly   326 FSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRS 390
            ..||::|...|:.|:...:::||:.|::.|.|:.:|:......|.||::.|...:..:.|::|.:
plant   295 LLAGVDTSGHTITWVMTHLIKNPRVMKKAQAEVREVIKNKDNITEEDIEGLEYLKMVVKETLRIN 359

  Fly   391 SIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY 455
            .:|||.|....::||::.||.||..:.:...|.::|.:||:|:.||.|.|.||:|.:...:...:
plant   360 PLVPLLTPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWKDPEAFIPERFMDNQIDYKGLNF 424

  Fly   456 -FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESF-KVCLK 518
             .:|||.|||:|.|..:....:.|...:.::.||..||||..:..:.       ..||: .||.|
plant   425 ELLPFGSGRRICPGIGMGMALIHLTLINLLYRFDWKLPEGMEVEDVD-------LEESYGLVCPK 482

  Fly   519 RRPL 522
            :.||
plant   483 KVPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	122/487 (25%)
CYP71B13	NP_197896.1	p450	1..490	CDD:299894	132/524 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000