DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B12

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_197895.1	Gene:	CYP71B12 / 832584	AraportID:	AT5G25130	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	137/515 - (26%)
Similarity:	246/515 - (47%)	Gaps:	50/515 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HLLMVFLGLLALVTLLQWLVRNYRELRK-LPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            ::::.|:...:::     :||..|:.:| |||||..||:||.|..:||:.|....:|::.||.|.
plant     5 YIIVAFVFFSSMI-----IVRIIRKTKKNLPPGPPRLPIIGNLHQLGSKPHRSMFKLSETYGPLM 64

  Fly    89 STRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDT--PFMQTLNGYGIINST-GKLWKDQRRFLH 148
            |.:.||..|||.|..:.::|..:.  .|...||:.  |...|.|...:..|. .|.|::.|:...
plant    65 SLKFGSVSTVVASTPETVKEVLKTFDVECCSRPNMTYPARVTYNLKDLCFSPYSKYWREVRKMTV 129

  Fly   149 DKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLH--ASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            .:|      |.....|..|.....||...:..:.  ||..:||:::..:.....:|||.:...
plant   130 VEL------YTAKRVQSFQHTRKEEVAALVDFIKQAASLEKPVNLNKKLMKLSGSVICRVAFG-- 186

  Fly   212 FSIDDPKFRR-FNFLIEEGMRLFGEIHTVDYIPTM-QCFPSISTAKNKIAQNRAEMQRFYQDVID 274
            .::...|... :..:|:..:.|.|.....||.|.: :....|:...:|..:....|..|:...|.
plant   187 INLQGSKLENTYEEVIQGTVELVGSFAAADYFPVVGRIIDRITGLHSKCEKLFKAMDAFFDQSIK 251

  Fly   275 DHKRSFDPNNIR-DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLL 338
            .|   .:...|: |::|..|   :..:.|.|..|....::|.:   .::.::.:||::|....:.
plant   252 HH---LEDEIIKDDIIDLLL---KMERGETTLGEFQLTRDHTK---GILANILNAGIDTSAQVMT 307

  Fly   339 WINVFMLRNPKEMRRVQDELDQVVGRHRLPTIED----LQYLPITESTILESMRRSSIVPLATTH 399
            |:..:::.||:.:::.|.|:.:|: :|:...||:    ||||   :..|.|:.|.:.:|||....
plant   308 WVMTYLISNPRVLKKAQAEVREVI-KHKDDIIEEDIERLQYL---KMVIKETFRINPLVPLLIPR 368

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGR 463
            ..::||::.||.||..:.:...|.::|.:||:|:.||.|.|.||:|::...:...: .:|||.||
plant   369 EASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWKDPEAFIPERFMDSQIDYKGLNFELLPFGSGR 433

  Fly   464 RMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESF-KVCLKRRPL 522
            |:|.|..:....:.|...:.::.||..||||.       .|......||: .||.|:.||
plant   434 RICPGIGMGMALVHLTLINLLYRFDWKLPEGM-------KVADVDLEESYGLVCPKKIPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	127/478 (27%)
CYP71B12	NP_197895.1	p450	1..490	CDD:386267	137/515 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000