DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp18a1 and CYP71B11

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_197894.1	Gene:	CYP71B11 / 832583	AraportID:	AT5G25120	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	134/512 - (26%)
Similarity:	242/512 - (47%)	Gaps:	44/512 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HLLMVFLGLLALVTLLQWLVRNYRELRK-LPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            ::::.|:....::     :|||.|:.:| |||||..||:||.|..:||:.|:...:|:::||.|.
plant     5 YIIVAFVFFSTII-----IVRNTRKTKKNLPPGPPRLPIIGNLHQLGSKPHSSMFKLSEKYGPLM 64

  Fly    89 STRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPF----MQTLNGYGIINSTGKLWKDQRRFL 147
            :.|.||..|||.|..:.::|..:.  .|...||...:    ...|...|....| |.|::.|:..
plant    65 ALRFGSVSTVVASTPETVKEVLKTFDAECCSRPYMTYPARLTYNLKDIGFCPYT-KYWREVRKMT 128

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL--HASDGQPVDMSPVISVAVSNVICSLMMST 210
            ..:|      |.....|..|.....||...:..:  .||..:||:::..:.....:|||.::..
plant   129 VVEL------YTAKRVQSFQHTRKEEVASLVDFITQAASLEKPVNLNTKLMKLSGSVICRVVFG- 186

  Fly   211 RFSIDDPKFRR-FNFLIEEGMRLFGEIHTVDYIPTM-QCFPSISTAKNKIAQNRAEMQRFYQDVI 273
             .::...|... :..:|:..|.:.|.....||.|.: :....|:...:|..:....|..|:...|
plant   187 -INLKGSKLENLYEEVIQGTMEVVGSFAAADYFPIIGRIIDRITGLHSKCEKIFKAMDAFFDQSI 250

  Fly   274 DDHKRSFDPNNIR-DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTL 337
            ..|   .:..:|: |::|..|      |.|..:.||.:.:...:....::.::.:||::|....:
plant   251 KHH---LEDESIKDDIIDLLL------KMERGEIELGEFQLTRDNTKGILFNILNAGIDTSAQVM 306

  Fly   338 LWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPT 402
            .|:..:::.||:.|::.|.|:.:|:........||::.|...:..:.|:.|...:|||......:
plant   307 TWVMTYLISNPRVMKKAQAEVREVIKNKDDIIEEDIERLEYLKMVVKETFRVLPLVPLLIPREAS 371

  Fly   403 RDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGRRMC 466
            :||::.||.||..:.:...|.::|.:||:|:.||.|.|.||:|.:...:...: |:|||.|||||
plant   372 KDVKIGGYDIPKKTWIHVNIWAIHRNPNVWKDPEAFIPERFMDNQIDYKGLNFEFLPFGSGRRMC 436

  Fly   467 LGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESF-KVCLKRRPL 522
            .|..:....:.|...:.::.||..||||..:..:.       ..||: .||.|:.||
plant   437 PGIGMGMALVHLTLINLLYRFDWKLPEGMEVEDVD-------LEESYGLVCPKKVPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	123/475 (26%)
CYP71B11	NP_197894.1	CYP71-like	59..486	CDD:410695	112/451 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910