DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP81D8

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_195453.1	Gene:	CYP81D8 / 829891	AraportID:	AT4G37370	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	127/506 - (25%)
Similarity:	236/506 - (46%)	Gaps:	63/506 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VFLGLLALVTLLQWLVRNYRELRKLPPGP-WGLPVIGYLLFMGSEKHTRFMELAKQYGS--LFST 90
            :...:|.:|..|.:|:...:....|||.| |.|||||:|..:....|..|:.|::...:  :||.
plant     6 LIFSILFVVLSLIYLIGKLKRKPNLPPSPAWSLPVIGHLRLLKPPIHRTFLSLSQSLNNAPIFSL 70

  Fly    91 RLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTLNGYG----IINSTGKLWKDQRR---- 145
            |||::|..|.|.:.:..|||.:.:  ...||:....:.: .|.    |..|.|..|::.||
plant    71 RLGNRLVFVNSSHSIAEECFTKNDVVLANRPNFILAKHV-AYDYTTMIAASYGDHWRNLRRIGSV 134

  Fly   146 --FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMM 208
              |.:.:|..|    :...|.::::.:......|     :.:...|||..::|....|.|..::.
plant   135 EIFSNHRLNSF----LSIRKDEIRRLVFRLSRNF-----SQEFVKVDMKSMLSDLTFNNILRMVA 190

  Fly   209 STRF----SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFY 269
            ..|:    ..|||:.:|...||.:.:...|..:.|||:|.::......|...|:|   ..:..|.
plant   191 GKRYYGDGVEDDPEAKRVRQLIADVVACAGAGNAVDYLPVLRLVSDYETRVKKLA---GRLDEFL 252

  Fly   270 QDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            |.::|:.:.:.:..|  .::| :|..:::::.:.....:..|.         ::.|..||.:|..
plant   253 QGLVDEKREAKEKGN--TMID-HLLTLQESQPDYFTDRIIKGN---------MLALILAGTDTSA 305

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            .||.|....:|.:|..:.:.:||:|:.:|..||....|:..||..::.:.|::|.....|:...|
plant   306 VTLEWALSNVLNHPDVLNKARDEIDRKIGLDRLMDESDISNLPYLQNIVSETLRLYPAAPMLLPH 370

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRR 464
            ..:.|.::.||.:|.|:.::..:.::|.||.||:.|..|:|.|| :.||:.:|   .:|||:|||
plant   371 VASEDCKVAGYDMPRGTILLTNVWAIHRDPQLWDDPMSFKPERF-EKEGEAQK---LMPFGLGRR 431

  Fly   465 MCLGDVLARMELFLFFASFMHCFD---------------IALPEGQPLPSL 500
            .|.|..||...:.|...|.:.|.:               :.:|:.:||.::
plant   432 ACPGSGLAHRLINLTLGSLIQCLEWEKIGEEVDMSEGKGVTMPKAKPLEAM 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	122/481 (25%)
CYP81D8	NP_195453.1	p450	5..487	CDD:299894	127/506 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000