DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP705A3

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_193271.5	Gene:	CYP705A3 / 827202	AraportID:	AT4G15360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	117/495 - (23%)
Similarity:	209/495 - (42%)	Gaps:	59/495 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VFLGLLALVTLL--QWLVRNYRELRK--LPPGPWGLPVIGYL-LFMGSEKHTRFMELAKQYGSLF 88
            :|: ||.|.:||  ....:..::.|.  ||..|..||:||:| |.:....|....:|:.:||.|.
plant    13 IFI-LLCLFSLLCHSLFFKKPKDSRSFVLPSSPPSLPIIGHLHLLLSVLTHKSLQKLSSKYGPLL 76

  Fly    89 STRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTL--NGYGIINST-GKLWKDQRRFLH 148
            ..|:.....:::|...|..|.|:..:  .:.|......::|  ...||:|:. |..||..::.:.
plant    77 LIRIFYVPIILVSSSSMAYEIFKAHDVNVSSRGIIALDESLMFGASGILNAPYGDYWKFMKKLMA 141

  Fly   149 DKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL--HASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            .||.:..:.....|.:      :.|:|.|...:  .|:..:.|::.......::|.:|.|:|...
plant   142 TKLLRPQVLERSRGVR------VEELHRFYRSILDKATKNESVEIGKEAMKLMNNTLCKLIMGRS 200

  Fly   212 FSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDH 276
            ||.|:.:..|...|::|...|..:|.....:........||..|.:|.....:.....:.::.:.
plant   201 FSEDNGESNRVRGLVDETYALSEKIFLAAILRRPLAKLRISLFKKEIMGVSNKFDELLERILQER 265

  Fly   277 KRSFDPNNIR--DLVDFYLCEIEKAKAEGTDAELFDGKNHE-----EQLVQVIIDLFSAGMETIK 334
            |.:.:..|..  |::|..|             |.:..:|.|     :.:....::.|..|.:|..
plant   266 KENLEEKNNEGMDMMDVLL-------------EAYGDENAEYKITWKHIKAFFVEFFIGGTDTSV 317

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            .|..|....|:.|...:.|:::|:..|||..||....||..||..::.:.|.:|         .|
plant   318 QTTQWAMAEMINNANVLERLREEIVSVVGETRLIQETDLPNLPYLQAVVKEVLR---------LH 373

  Fly   400 SPT--------RDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPE-- 454
            .|:        ...|:.|:.||..:.:|..:.::..|.:.||.||:|:|.||:.:.....:.|
plant   374 PPSPVLIRKFQEKCEVKGFYIPEKTTLIVNVYAIMRDSDSWEDPEKFKPERFLTSSRSGEEDEKE 438

  Fly   455 -YFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493
             .|:|||.|||.|.|..|..:.:.......:.|||..:.|
plant   439 LKFLPFGSGRRGCPGANLGSIFVGTAIGVMVQCFDWKIKE 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	109/466 (23%)
CYP705A3	NP_193271.5	p450	15..509	CDD:299894	116/493 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910