DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71A20

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_193067.3	Gene:	CYP71A20 / 826961	AraportID:	AT4G13310	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	120/461 - (26%)
Similarity:	201/461 - (43%)	Gaps:	52/461 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LALVTLLQWLVRNY--RELRK---LPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLG 93
            |.|.|||..|:::.  |...|   |||.||.|||||.|..:....|.....|:.:||.|.....|
plant     8 LCLTTLLALLLKSILKRTATKNFNLPPSPWRLPVIGNLHQLSLHTHRSLRSLSLRYGPLMLLHFG 72

  Fly    94 SQLTVVMSDYKMIRECFRREEF--TGRPDTPFMQTLNGYG---IINSTGKLWKDQRRFLHDKLRQ 153
            ....:::|...:..:..:..:.  ..||.|..:..:...|   .....|:.|:..:......|
plant    73 RTPVLIVSSADVAHDVMKTHDLVCANRPKTKVVDKILSGGRDVAFAPYGEYWRQMKSICIQNL-- 135

  Fly   154 FGMTYMGNGKQQMQKRIM-TEVHEFIGHLH----ASDGQPVDMSPVISVAVSNVICSLMMSTRFS 213
                 :.|...:..::|. .|:...|..|.    :|...||::|.::....:::||.:.:..::|
plant   136 -----LNNKMVRSYEKIREEEIKRMIEKLEKASCSSSPSPVNLSQILMTLTNDIICRVALGRKYS 195

  Fly   214 -----IDDPKFRRFNFLIEEGMRLF----GEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFY 269
                 ||          :|..:|.|    ||....:|||::.....|....:|:.........|.
plant   196 GKKDGID----------VENIVRTFAALLGEFPVGEYIPSLSWIDRIRGLDHKMEVVDKRFDEFL 250

  Fly   270 QDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            :.|:.:|:.: |.....|||| .|..|:..|....:.|       :..|..:|.|:|.||..|..
plant   251 ERVVKEHEEA-DKETRSDLVD-KLLTIQSDKTGQFELE-------KSALKLIIWDMFLAGTATTL 306

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            :.|.|....::||||.|:::|:|:.....:....|.::.:.:...::.|.|::|.....||....
plant   307 SFLEWAMTELMRNPKVMKKLQEEIRSSSPQDLFVTEKEAEKMNYLQAVIKEALRLRPPAPLLVPR 371

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLW-EKPEEFRPSRFIDTEGKVRKPEY-FIPFGVG 462
            ..:.||:|.||.||||:.||....::..|...| ...|||:|.|.:||....:..:: |||||.|
plant   372 VLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGTDAEEFKPERHLDTNLDFQGQDFKFIPFGSG 436

  Fly   463 RRMCLG 468
            :|:|.|
plant   437 KRICPG 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	111/436 (25%)
CYP71A20	NP_193067.3	p450	24..494	CDD:299894	114/445 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910