DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP706A7

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_192970.1	Gene:	CYP706A7 / 826842	AraportID:	AT4G12330	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	138/506 - (27%)
Similarity:	240/506 - (47%)	Gaps:	41/506 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 WL-VRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKM 105
            |: |::.|....|||||.|||::|.|.|:..|.||.|..||:::|.:|...||::||:|::..:.
plant    34 WVYVKSKRLFPPLPPGPRGLPIVGNLPFLHPELHTYFHSLAQKHGPVFKLWLGAKLTIVITSSEA 98

  Fly   106 IRECFRREE-FTGRPDTPFMQTLNGYG----IINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQ 165
            .|:..|..: .....|.|...:|:.||    :.:..|..|...|:...:|:.. ..|...|....
plant    99 TRDILRTNDVIFANDDVPVAGSLSTYGGVDIVWSPYGPEWPMLRKICINKMLS-NATLDSNSFSA 162

  Fly   166 MQKRIMTEVHEFIGHL--HASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFR---RFNFL 225
            ::::   |....:.:|  .|..|..|::...|.|.:.||:..::.....:.|:.:.:   .|..|
plant   163 LRRQ---ETRRTVRYLADRARAGLAVNVGEQIFVTILNVVTQMLWGETVADDEEREKVGAEFLEL 224

  Fly   226 IEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVD 290
            |.|.:.:.|:.:..|:.|.:..|.....|| ::.::...|.|.:..:| ..:...|..:..:..|
plant   225 ITEIIDVVGKPNVSDFFPVLSRFDLQGLAK-RVRRSAQRMDRMFDRII-SQRMGMDKGSKGNGGD 287

  Fly   291 FYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQ 355
            | |..:..||.|..:..:    ||.:.|   ::|:...|.:|...|:.:....::...:.|:|.|
plant   288 F-LMVLLNAKDEDENMSM----NHVKAL---LMDMVLGGTDTSLNTIEFAMAELINKLEIMKRAQ 344

  Fly   356 DELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIP 420
            .|||:|||::.:...:.:..||...|.:.|::|....:||.....|:....:.|||||..|.|..
plant   345 QELDKVVGKNNIVEEKHITKLPYILSIMKETLRLHPALPLLIPRCPSETTVIGGYTIPNDSKVFI 409

  Fly   421 LINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGRRMCLGDVLARMELFLFFASFM 484
            .:.::|.:||:||.|.||.|.||:|........:| :.|||.|||:|.|..:|...:....|:.:
plant   410 NVWAIHRNPNVWENPLEFNPDRFLDKGYDFSGNDYSYFPFGSGRRICAGMAMAEKVVLYNLATLL 474

  Fly   485 HCFDIALPEGQPLPSLKGNVGATITPESFKVCLK-RRPLGPT----AADPH 530
            |.||..:.||:.:.          ..|.|.:.|| :.||..|    .:||:
plant   475 HSFDWRIGEGEKVE----------LEEKFGILLKLKNPLVATPVLRLSDPN 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	127/473 (27%)
CYP706A7	NP_192970.1	p450	55..517	CDD:299894	127/485 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000