DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP706A4

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_192967.1	Gene:	CYP706A4 / 826839	AraportID:	AT4G12300	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	140/508 - (27%)
Similarity:	236/508 - (46%)	Gaps:	46/508 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLT 97
            :|..|..:.|.:........|||||.|||::|.|.|:..:.||.|..||:.:|.:|...|||:||
plant    22 ILTTVFSILWYIFKRSPQPSLPPGPRGLPIVGNLPFLDPDLHTYFANLAQSHGPIFKLNLGSKLT 86

  Fly    98 VVMSDYKMIRECFRREE--FTGRPDTPFMQTLNGYGIINST----GKLWKDQRRFLHDKL---RQ 153
            :|::...:.||..:.::  |:.| |.|.......||.|:..    |..|:..|:....||   :.
plant    87 IVVNSPSLAREILKDQDINFSNR-DVPLTGRAATYGGIDIVWTPYGAEWRQLRKICVLKLLSRKT 150

  Fly   154 FGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQ--PVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            ....|      :::::   ||.|...:|:....:  ||.:...:.:.:.|:..:::.......::
plant   151 LDSFY------ELRRK---EVRERTRYLYEQGRKQSPVKVGDQLFLTMMNLTMNMLWGGSVKAEE 206

  Fly   217 PKF--RRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHK-- 277
            .:.  ..|..:|.|..||..|.:..|:.|.:..|......| ::.....|:.......|:..|
plant   207 MESVGTEFKGVISEITRLLSEPNVSDFFPWLARFDLQGLVK-RMGVCARELDAVLDRAIEQMKPL 270

  Fly   278 RSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINV 342
            |..|.:.::|.:.:.:    |.|.:..|:|:....||.:.|   :.|:...|.:|...|:.:...
plant   271 RGRDDDEVKDFLQYLM----KLKDQEGDSEVPITINHVKAL---LTDMVVGGTDTSTNTIEFAMA 328

  Fly   343 FMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVEL 407
            .::.||:.::|.|:|||:|||:..:.....:..||...:.:.|::|....:||...|.|..:..:
plant   329 ELMSNPELIKRAQEELDEVVGKDNIVEESHITRLPYILAIMKETLRLHPTLPLLVPHRPAENTVV 393

  Fly   408 NGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEG-KVRKPEY-FIPFGVGRRMCLGDV 470
            .|||||..:.:...:.|:..|||:||.|.||||.||:|... ......| :.|||.|||:|.|..
plant   394 GGYTIPKDTKIFVNVWSIQRDPNVWENPTEFRPERFLDNNSCDFTGANYSYFPFGSGRRICAGVA 458

  Fly   471 LARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR-PL 522
            ||...:....|:.:|.||..:|||..| .||         |.|.:.||.: ||
plant   459 LAERMVLYTLATLLHSFDWKIPEGHVL-DLK---------EKFGIVLKLKIPL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	132/479 (28%)
CYP706A4	NP_192967.1	p450	17..512	CDD:386267	140/508 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3251
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000