DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B31

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_190898.1	Gene:	CYP71B31 / 824497	AraportID:	AT3G53300	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	127/503 - (25%)
Similarity:	218/503 - (43%)	Gaps:	57/503 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELR-KLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            :.:|||||.|..|...|.:|....| ||||||.|||:||.|..:|...|:...:|:.::|.:...
plant     1 MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLV 65

  Fly    91 RLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLN------------GYGIINST--GKLWK 141
            |.|.....|.|..:..:|..:..:         ::|.|            ||..|..|  |:.|:
plant    66 RWGVVPMAVFSSNEAAKEVLKTHD---------LETCNRPKLVANGLFTHGYKDIGFTQYGEEWR 121

  Fly   142 DQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQP---VDMSPVISVAVSNVI 203
            :.::|:       |:......|.:..:.|..|..:.:....::..|.   ||:...:....:::|
plant   122 EMKKFV-------GLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASII 179

  Fly   204 CSLMMSTRF-SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQ- 266
            ........| ..|.....:...|::|.......:...|:.|.     .:....::|:...:.|.
plant   180 FREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPR-----GLGWLVDRISGQHSRMNI 239

  Fly   267 ------RFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDL 325
                  .|::||||:..::...::..|||...|..|.:.:..|:....:|      .|:.::.|:
plant   240 AFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYD------HLIAMMSDV 298

  Fly   326 FSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVG--RHRLPTIEDLQYLPITESTILESMR 388
            ..||:.....|::|....:.|:|:.|:::|:|:...:|  :.|: |.|||:.:......|.||.|
plant   299 VLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERI-TEEDLEKVEYLNLVIKESFR 362

  Fly   389 RSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKP 453
            .....||........|:|:.||.||..:||.....::..||..|..||||.|.||::|....:..
plant   363 LHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQ 427

  Fly   454 EY-FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSL 500
            .| .:|||.|||.|.|..|....|.|...:.::.||.:||.|..:..:
plant   428 HYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	115/475 (24%)
CYP71B31	NP_190898.1	CYP71-like	58..491	CDD:410695	102/446 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900