DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B5

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_190896.1	Gene:	CYP71B5 / 824495	AraportID:	AT3G53280	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	489	Identity:	126/489 - (25%)
Similarity:	218/489 - (44%)	Gaps:	43/489 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LMVFLGLLALVTL-LQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            :.:||..|.|:.| |.:|.:......||||||.|||:||.|...|...|....:::::||.:...
plant     1 MSIFLCFLLLLPLSLIFLKKLLPSKGKLPPGPKGLPIIGNLHQFGRFLHKSLHKISQEYGPVMLL 65

  Fly    91 RLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTLNGYGIINST---------GKLWKDQR 144
            ..|....:::|..:...|..:..  |...||.|.      |.|:....         |:.|::.|
plant    66 HFGVVPVIIVSSKEGAEEVLKTHDLETCSRPKTV------GSGLFTYNFKDIGFAPYGENWREMR 124

  Fly   145 R------FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVI 203
            :      |...||:.|  .|:...:.|:..|.:::      ....:....|::..||....:::|
plant   125 KIAVSELFSQKKLKSF--RYIREDESQLLVRKVSK------SALETPTSSVNLRKVIFTFAASII 181

  Fly   204 CSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRF 268
            |.|.....| .|.........|:.|.....|.:...|::|.......||...:.:.:..:::..|
plant   182 CRLSFGQNF-CDFVDMETVEELVLESETNLGSLAFADFLPAGWIIDRISGQHSTVMKAFSKLTNF 245

  Fly   269 YQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
            ::.|||||.:|....:..|::...|..|.|      ..|:...|..::.|..::.|:|.||:...
plant   246 FELVIDDHLKSGKIEDHSDIISVMLDMINK------PTEVGSYKVTDDHLKGLMSDVFLAGVNAG 304

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP-TIEDLQYLPITESTILESMRRSSIVPLAT 397
            ..|::|....:.|:|:.||::|:|:...:|.::.. |.|||:.:...:..|.|:.|.....||..
plant   305 SITMIWTMTELSRHPRVMRKLQEEIRAALGPNKEKITEEDLEKVEYLKMVIEEAFRLHPPAPLLL 369

  Fly   398 THSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYF--IPFG 460
            ......|:.:.||:||..:.:.....::..||..|.||:||.|.||:|...:. |.::|  :|||
plant   370 PRLTMSDINIQGYSIPKNTMIQINTYTIGRDPKNWTKPDEFIPERFVDNPIEY-KGQHFELLPFG 433

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPEG 494
            .|||:|.|.......:.|...|.::.||.:||.|
plant   434 AGRRVCPGMATGITIVELGLLSLLYFFDWSLPNG 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	117/461 (25%)
CYP71B5	NP_190896.1	CYP71-like	58..489	CDD:410695	105/432 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900