DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71A21

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_680111.1	Gene:	CYP71A21 / 823990	AraportID:	AT3G48320	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	119/483 - (24%)
Similarity:	223/483 - (46%)	Gaps:	45/483 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTR 91
            :::...|:..:|:|.:..:...:....|..|..||:||.|..:|...|.....|:.:||.|....
plant     6 MIILQSLIIFITILFFKKQKRGKKSNTPRSPPRLPLIGNLHQLGHHPHRSLCSLSHRYGPLMLLH 70

  Fly    92 LGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTL--NGYGIINST-GKLWKDQR-----RF 146
            ||....:|:|...:.|:..:..:  |..||.:...:.|  :|..:..:. |:.|:..:     |.
plant    71 LGRVPVLVVSSADVARDILKTHDRVFASRPRSKLFEKLFYDGRDVAFAPYGEYWRQIKSVCVLRL 135

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            |.:|:    :|...|.:|:       |:...:..:..|....|::|.::....::||..:.:..:
plant   136 LSNKM----VTSFRNVRQE-------EISLMMEKIQKSSSLQVNVSELLGSLTNDVISRIALGRK 189

  Fly   212 FSID-DPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDD 275
            :|.: |.|     .|::..|.|.||.....|:|.:.....||....::.:...::..|.:.|:.|
plant   190 YSGETDSK-----ELMKRLMMLMGEFSVGTYVPWLGWIDWISGLDGQLNKTGNDLDEFLEKVVQD 249

  Fly   276 HKRSFDPNNIR-DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLW 339
            |   .|.:..| |.|| .|..|::.|:.|.:.:....|       .:::|:..||.::....:.|
plant   250 H---VDGDGQRTDFVD-VLLRIQREKSIGFEIDRLCIK-------AIVLDVLVAGTDSSYALMDW 303

  Fly   340 INVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRD 404
            ....:||:|:.:|.:|:|:..:...:...:.||:|.:...::.|.|:.|....:||...|...:|
plant   304 AMTELLRHPECLRTLQEEVRTICKGNLSVSEEDIQNMSYLKAVIKETTRLHPPLPLLAPHESIQD 368

  Fly   405 VELNGYTIPAGSHVIPLIN--SVHMDPNLW-EKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGRRM 465
            |.|..|.||||:.|  :||  ::..:...| ...|:|||.|.:|:....|...: .:|||.|||:
plant   369 VILGDYHIPAGTQV--MINAWAIGREAATWGPDAEKFRPERHLDSSVDFRGHNFELVPFGAGRRI 431

  Fly   466 CLGDVLARMELFLFFASFMHCFDIALPE 493
            |.....|.:.:.:..|:|:|.:|..|||
plant   432 CPAISFAVVLIEVALANFVHRYDWKLPE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	116/456 (25%)
CYP71A21	NP_680111.1	p450	1..482	CDD:299894	119/483 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000