DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71A22

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_680110.1	Gene:	CYP71A22 / 823989	AraportID:	AT3G48310	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	118/488 - (24%)
Similarity:	220/488 - (45%)	Gaps:	57/488 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRL 92
            ::.|.|:..:|:|.::.:...:....|..|..||:||.|..:|...|.....|:.:||.|...|.
plant     7 IILLSLIIFITILFFIKQKKGKKSNTPASPPRLPLIGNLHQLGRHPHRSLCSLSNRYGPLMLLRF 71

  Fly    93 GSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQ---------TLNGYGIINSTGKLWKDQR-- 144
            |....:|:|...:.|:..:..:  |..||.:...:         .|..|      |:.|:..:
plant    72 GLVPVLVVSSADVARDILKTYDRVFASRPRSKIFEKIFYEARDVALAPY------GEYWRQMKSV 130

  Fly   145 ---RFLHDKL-RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICS 205
               ..|.:|: |.|     .|.:|:       |:...:..:..|....|::|.::....::||..
plant   131 CVLHLLTNKMVRSF-----RNVRQE-------EISLMMEKIQKSSSLQVNLSELLGSLTNDVISR 183

  Fly   206 LMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQ 270
            :.:..::| |:..|:.   |::...:|.||.....|:|.:.....||....::.:...::..|.:
plant   184 VALGRKYS-DETDFKE---LMKRLTKLLGEFCVGTYVPWLAWIDWISGLDGQLKKTGNDLDEFLE 244

  Fly   271 DVIDDHKRSFDPNNIR-DLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            .|:.||:   |.:..| |.|| .|..|::.|:.|.:.:....|       .:|:|:...|.:|..
plant   245 KVVQDHE---DGDAQRTDFVD-VLLRIQREKSVGFEIDRLSIK-------AIILDVVVGGTDTSY 298

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            ..:.|....:|..|:.:.|:|:|:..:...:...:.:|::.:...::.|.|:||....:||...|
plant   299 ALMEWAMTELLHRPECLNRLQEEVRTICKGNSSVSEDDIKDMNYLKAVIKETMRLHPPLPLMVPH 363

  Fly   400 SPTRDVELNGYTIPAGSHVIPLIN--SVHMDPNLW-EKPEEFRPSRFIDTEGKVRKPEY-FIPFG 460
            ..|:||.|..|.||||:.|  :||  ::..:...| ...|:|||.|.:::....|...: .||||
plant   364 ESTQDVRLGDYHIPAGTQV--MINAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNFELIPFG 426

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493
            .|||:|.....|.:.:.:..|:.:|.:|..|||
plant   427 AGRRICPAISFAVILIEVTLANLVHRYDWRLPE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	114/462 (25%)
CYP71A22	NP_680110.1	p450	24..482	CDD:299894	114/471 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000