DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71A23

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001325471.1	Gene:	CYP71A23 / 823988	AraportID:	AT3G48300	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	479	Identity:	117/479 - (24%)
Similarity:	217/479 - (45%)	Gaps:	43/479 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLP--PGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            ::::||.|:.|..:.....:.::.:.|:.  |.|..||:||.|..:....|.....|:.:||.|.
plant     2 IMILFLCLIILFIITILFFKKHKTVNKIINFPSPPRLPLIGNLHQLSQHPHRSLCYLSHRYGPLM 66

  Fly    89 STRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTLNGYGIINST----GKLWKDQR--- 144
            ....||...:|.|..:..|:..:..:  |..||.:...:.|. |...|..    |:.|:..:
plant    67 LLHFGSVPVIVASTAEAARDVLKTHDRVFASRPRSKIFEKLL-YKSRNMASAPYGEYWRQMKSVS 130

  Fly   145 --RFLHDKL-RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSL 206
              ..|.:|: |.|         |.:::..:|.:.|.|   ..|..:||::|.::|...::|||.:
plant   131 VLHLLSNKMVRSF---------QDVRQEEITLMMETI---RKSSSKPVNLSKILSSLTNDVICRV 183

  Fly   207 MMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQD 271
            .:..::.:...    |..||:..||..|......|:|.:.....:|..:.::.:...:..:..:.
plant   184 ALGRKYGVGTD----FKELIDRLMRQLGTFTIGSYVPWLAWTDWVSGLEARLEKTANDFDKLLER 244

  Fly   272 VIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTT 336
            ::.||:..  ..:..|.||..|. .::.|:.|.|.:....|       .:::|.|..|.:|..|.
plant   245 IVQDHEDG--DGDKTDFVDVLLA-AQRDKSFGFDIDRLSIK-------AIVLDAFVGGTDTSSTL 299

  Fly   337 LLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSP 401
            :.|....:||:|..::::|:|:..:.......:.:|:|.:...::.:.|::|....|||...|..
plant   300 VEWEMTELLRHPTCLKKLQEEVRTICKGKSSVSEDDIQGMEYLKAVVKEALRLHPPVPLMVPHQS 364

  Fly   402 TRDVELNGYTIPAGSHVIPLINSVHMDPNLW-EKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGRR 464
            |:||.|....||||:.||..:.:|..:...| ....||||.|.:::....|..:: .||||.|||
plant   365 TQDVRLRDNHIPAGTQVIVNLWAVGREAATWGPDANEFRPERHLESPSDFRGQDFELIPFGAGRR 429

  Fly   465 MCLGDVLARMELFLFFASFMHCFD 488
            ||.|...|.:...:..|:.:|.||
plant   430 MCPGISFAVVLNEVVLANLVHGFD 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	112/451 (25%)
CYP71A23	NP_001325471.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910