DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71A24

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001190031.2	Gene:	CYP71A24 / 823987	AraportID:	AT3G48290	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	128/515 - (24%)
Similarity:	220/515 - (42%)	Gaps:	79/515 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLMVFLGL--LALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            ::|:.|.|  :.|:|:|.:..::..:....||.|..||:|..|..:|...|.....|:.:||.|.
plant     4 MMMIILLLCSIILITILFFKKQSRGKKSNAPPSPPRLPLIRNLHQLGRHPHRSLCSLSHRYGPLM 68

  Fly    89 STRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTL--NGYGI-INSTGKLWKDQRR--- 145
            ....||...:|:|.....::..:..:  |..||.:.....:  ||..: :...|:.|:..:.
plant    69 LLHFGSVPVLVVSSADAAKDVLKTHDRVFASRPRSKIFDKIFYNGRDVALAPYGEYWRQMKSVCV 133

  Fly   146 ---FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLM 207
               |.:..:|.|        :...|:    |:...|..:..|....:::|.::....:||||.:.
plant   134 LHLFSNKMVRSF--------RDVRQE----EISLMIEKIRISSSLRINLSEILVNLTNNVICRVA 186

  Fly   208 MSTRF--SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQ 270
            :..::  ..|      |..|::...||.||.....|:..:.....|.....::.:...::..|.:
plant   187 LGRKYGGKTD------FKDLMKRLTRLLGEFSVGSYVSWLAWIDWIRGLDGQLIKISNDLDEFLE 245

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAE--------LFDGK-------------NH 314
            .|:.||.......|  |.||| |..||:.|:.|.:.:        |..|:             ||
plant   246 RVVQDHVDGDGHKN--DFVDF-LLTIEREKSVGFEIDRLSIKAIILVKGRYENKFKFTDELVYNH 307

  Fly   315 EE----QLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQY 375
            ..    |      |:|...|:|..|.|.|....:|.:.:.:.|:|:|:..|.......:.:|||.
plant   308 SSCFGFQ------DVFVGDMDTTYTLLEWAMTELLCHHECLDRLQEEVRMVCKDKSGVSEDDLQD 366

  Fly   376 LPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLIN--SVHMDPNLW-EKPEE 437
            :...::.|.|::|....:||...|..|.||:|..|.||||:||  :||  ::..:...| ...||
plant   367 MKYLKAVIKETLRLHPPLPLMVPHESTHDVKLRDYHIPAGTHV--MINAWAIGREAATWGPDAEE 429

  Fly   438 FRPSR----FIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493
            |||.|    ::|..|:..:   .:|||.|||:|.....|.:...:..|:.:|.||..|||
plant   430 FRPERHLNSYVDYRGQDTE---LVPFGAGRRICPAISFAVVLDEVVLANLVHQFDWTLPE 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	122/485 (25%)
CYP71A24	NP_001190031.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000