DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B37

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189264.3	Gene:	CYP71B37 / 822237	AraportID:	AT3G26330	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	128/491 - (26%)
Similarity:	215/491 - (43%)	Gaps:	51/491 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            |.::||..|.|..|   .::..|:.::.||.|.|.|:||.|..:|...|.....|:|:||.:...
plant     7 LPLLFLSCLLLAAL---RLKKRRQHQRKPPSPPGFPIIGNLHQLGELPHQSLWSLSKKYGPVMLL 68

  Fly    91 RLGSQLTVVMSDYKMIRE--------CFRREEFTGRPDTPFMQTLNGYGIINST-GKLWKDQRRF 146
            :.||..|||:|..:..::        |..|....|    |...:.|...|:.|. ...||:.||.
plant    69 KFGSIPTVVVSSSETAKQALKIHDLNCCSRPSLAG----PRALSYNYLDIVFSPFNDYWKELRRM 129

  Fly   147 LHDKLRQFGMTYMGNG-KQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMST 210
            ...:|......::... :::..|::|....|     .|:...||::|..::.....|||......
plant   130 CVQELFSPKQVHLIQPIREEEVKKLMNSFSE-----SAAQKTPVNLSEKLASLTVGVICKAAFGV 189

  Fly   211 RFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQR-------F 268
            .|.........|:.||.:.....|.....||      ||::....:.:...:.:.:|       |
plant   190 SFQGTVLNSDNFDKLIHDAFLFLGSFSASDY------FPNVGWIIDWLTGLQGQRERSVRGLDAF 248

  Fly   269 YQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
            |:.:.|.||:. :...:.|.||..|      |.|..:..|..||.....:..|::::...|:.|.
plant   249 YEQMFDLHKQG-NKEGVEDFVDLLL------KLEKEETVLGYGKLTRNHIKAVLMNVLLGGIGTS 306

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            ..|:.|....::|||:.|::||.|:...:|...:..::|:..|...:..|.|:.|.....||...
plant   307 AITMTWAMTELMRNPRVMKKVQSEIRNQIGGKSMICLDDIDQLHYLKMVINETWRLHPPAPLLVP 371

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPFGVG 462
            .....:.|:|||||||.:.:...:..:..||:.|:.||||.|.||:::....:...: .:|||.|
plant   372 REVMSEFEINGYTIPAKTRLYVNVWGIGRDPDTWKDPEEFLPERFVNSNIDAKGQNFELLPFGSG 436

  Fly   463 RRMC----LGDVLARMELFLFFASFMHCFDIALPEG 494
            ||||    :|..:....|    |:.::.||..||||
plant   437 RRMCPAMYMGTTMVEFGL----ANLLYHFDWKLPEG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	121/463 (26%)
CYP71B37	NP_189264.3	p450	26..498	CDD:299894	122/469 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000