DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B36

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189263.1	Gene:	CYP71B36 / 822236	AraportID:	AT3G26320	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	126/498 - (25%)
Similarity:	212/498 - (42%)	Gaps:	64/498 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MVFLGLLAL--VTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            ::||.||.|  :.|..:..:..::.::.||.|.|.|:||.|..:|...|.....|:|:||.:...
plant     4 ILFLSLLFLSCILLAAFTHKKRQQHQRKPPSPPGFPIIGNLHQLGELPHQSLWRLSKKYGHVMLL 68

  Fly    91 RLGSQLTVVMSDYKMIRE--------CFRREEFTGRPDTPFMQTLNGYGIINST-GKLWKDQRR- 145
            :.||..|||:|..:..::        |..|....|    |...:.|...|..|. ...||:.||
plant    69 KFGSIPTVVVSSSETAKQVLKIHDLHCCSRPSLAG----PRALSYNYLDIAFSPFDDYWKELRRI 129

  Fly   146 -----FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICS 205
                 |...:::.|...     |:...|:::..|.|     .||.|.||::|...:.....|.|.
plant   130 CVQELFSVKRVQSFQPI-----KEDEVKKLIDSVSE-----SASQGTPVNLSEKFTSLTVRVTCK 184

  Fly   206 LMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPT----MQCFPSISTAKNKIAQNRAEMQ 266
            ......|........||..||.:.....|.....||.|.    :.....:...:.:..:   .:.
plant   185 ATFGVNFQGTVLNSDRFEKLIHDTYLFLGSFSASDYFPNGGWIIDWLTGLHGQRERSVR---ALD 246

  Fly   267 RFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGME 331
            .||:.:.|.||:. :...:.|.||..|      :.|..:..:..||.....:..:::::...|:.
plant   247 AFYEQMFDLHKQG-NKEGVEDFVDLLL------RLEKEETVIGYGKLTRNHIKAILMNVLIGGIG 304

  Fly   332 TIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLA 396
            |...|:.|....::|||:.|::||.|:...:|:..:.|::|:..|...:..|.|:.|.....|..
plant   305 TSAITMTWAMTELMRNPRVMKKVQSEIRNQIGKKSMITLDDIDQLHYLKMVINETWRLHPPSPFL 369

  Fly   397 TTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF----IDTEGKVRKPEYF- 456
            .......:.|||.|.||..:.:...:.::..||:.|:.||||.|.||    ||.:|     ::|
plant   370 IPRQVMSEFELNDYVIPVKTRLYVNVWAIGRDPDTWKDPEEFLPERFVNSSIDAKG-----QHFE 429

  Fly   457 -IPFGVGRRMC----LGDVLARMELFLFFASFMHCFDIALPEG 494
             :|||.|||||    :|..:....|    |:.::.||..:|.|
plant   430 LLPFGSGRRMCPAMYMGTTMVEFGL----ANMLYHFDWKIPVG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	120/470 (26%)
CYP71B36	NP_189263.1	p450	20..498	CDD:299894	120/482 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910