DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B35

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189262.1	Gene:	CYP71B35 / 822235	AraportID:	AT3G26310	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	133/521 - (25%)
Similarity:	226/521 - (43%)	Gaps:	54/521 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MVFLGLLALVTLLQWLVRNYRELRKLP-----PGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSL 87
            |..:.||.|:.|:..|:..:.. :|.|     |.|.|.|:||.|..:|...|....:|:|:||.:
plant     1 MAHIWLLPLIFLVCILLAVFNH-KKHPKYRQFPCPPGFPIIGNLHQIGELPHQTLWKLSKKYGPV 64

  Fly    88 FSTRLGSQLTVVMSDYKMIRE--------CFRREEFTGRPDTPFMQTLNGYGIINST-GKLWKDQ 143
            ....||...|||:|.....|:        |..|...:|    |...:.|...|..|. ...||:.
plant    65 MHLMLGRVPTVVVSSSDTARQVLRVHDLHCCTRPSLSG----PRELSYNYLDIAFSPYDDYWKEV 125

  Fly   144 RRFLHDKLRQFGMTY-MGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLM 207
            |:....:|......: :...|.:..|:::..:.|     .||...||:::........:|:|...
plant   126 RKLCVQELFSTKQVHSIQPIKDEEVKKMIDSIAE-----SASQKNPVNLNNKCLELTVSVVCRTA 185

  Fly   208 MSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTA-KNKIAQNRAEMQRFYQD 271
            ....|........|||.::.|.:.:.|.....|:||.:.....:.|. :.:..:::.::..|::.
plant   186 FGVSFEGTVLNSDRFNKIVREALEMLGSFSAADFIPYVGWIIDVLTGLQGRRERSKRDLNAFFEQ 250

  Fly   272 VIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTT 336
            :.|.||......| .|.||..|      :.|..:|.|.:.|.....:..:::|:..||::|...|
plant   251 MFDLHKEGKKEGN-EDFVDLLL------RLEKEEAVLGNDKLTRNHIKAILLDVLLAGIDTSAIT 308

  Fly   337 LLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSP 401
            :.|....:.|||:.|::||.|:...:|...:.:.||:..|...:..|.|:.|.....||......
plant   309 MTWAMTELARNPRVMKKVQSEIRTQMGNRSMISFEDMDQLEYLKMVIKETWRLHPTTPLLLPREA 373

  Fly   402 TRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYF--IPFGVGRR 464
            ..:.::||||||..:.:...:.::..||:.|:.||.|.|.||:|..... |.::|  :|||.|||
plant   374 MSEFDINGYTIPVKTRLHVNVWAIGRDPDTWKDPEVFLPERFMDNNIDA-KGQHFELLPFGGGRR 437

  Fly   465 MC----LGDVLARMELFLFFASFMHCFDIALPEG--------QPLPSLKGNV--GATITPESFKV 515
            :|    :|..:....|    |:.::.||..||||        :..|.|..|.  ...:.||..:.
plant   438 ICPAIYMGTTMVEFGL----ANLLYHFDWKLPEGVEVKDIDVEEAPGLTVNKKNELLLVPEMRRS 498

  Fly   516 C 516
            |
plant   499 C 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	126/495 (25%)
CYP71B35	NP_189262.1	p450	7..496	CDD:386267	130/510 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910