DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B34

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189261.1	Gene:	CYP71B34 / 822234	AraportID:	AT3G26300	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	133/527 - (25%)
Similarity:	239/527 - (45%)	Gaps:	57/527 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MVFLGLLALVTLLQWLV-----RNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSL 87
            |..:.||:|:.::..||     :|.|..::.||.|.|.|:||.|..:|...|....:|:|:||.:
plant     1 MTNIWLLSLIFVICILVAVFNHKNRRNYQRTPPSPPGCPIIGNLHQLGELPHQSLWKLSKKYGPV 65

  Fly    88 FSTRLGSQLTVVMSDYKMIRE--------CFRREEFTGRPDTPFMQTLNGYGIINST-GKLWKDQ 143
            ...:||...||::|..:..::        |..|..|.|..:..:    |...|..|. ...||:.
plant    66 MLLKLGRVPTVIVSSSETAKQALKIHDLHCCSRPGFAGARELSY----NYLDIAFSPYDDYWKEV 126

  Fly   144 RRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQ--PVDMSPVISVAVSNVICSL 206
            |:....:|      :.......:|.....||.:.|..:..|..|  |::::..:.....:|:|..
plant   127 RKLAVQEL------FSSKQVHSIQPIKDEEVKKLIDSISESAAQKTPINLNKTLLALTVSVVCRT 185

  Fly   207 MMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTM-QCFPSISTAKNKIAQNRAEMQRFYQ 270
            ..|..|........|||.::.|.:.:.|.....|:||.: :....::..:.:..::..::..||:
plant   186 AFSVNFEGTVLNSERFNNIVREALEMLGSFSASDFIPYVGRIIDLLTGLQGRRERSMRDLDAFYE 250

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKT 335
            .:.|.||:..:..: .|.||..|      :.|..:|.|.:.|.....:..:::|:..|||:|...
plant   251 QMFDLHKQKKEEGS-EDFVDLLL------RLEKEEAVLGNDKLTRNHIKAILMDVLLAGMDTSAI 308

  Fly   336 TLLWINVFMLRNPKEMRRVQDEL-DQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            |:.|....:.:||:.|::||.|: .|:..:.|: :.:|...|...:..|.|:.|.....||....
plant   309 TMTWAMAELAKNPRVMKKVQSEIRSQIKNKERI-SFDDTDKLEYLKMVIKETWRLHPTTPLLIPR 372

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF----IDTEGKVRKPEYF--IP 458
            ....:.|:||||||..:.:...:.::..||:.|:.||.|.|.||    ||.:|     ::|  :|
plant   373 EAMSEFEINGYTIPVKTRLHVNVWAIGRDPDTWKDPEVFLPERFTDNNIDAKG-----QHFELLP 432

  Fly   459 FGVGRRMC----LGDVLARMELFLFFASFMHCFDIALPEGQPLP--SLKGNVGATITPESFKVCL 517
            ||.|||||    :|..:....|    |:.::.||..||||..:.  .::...|.|:..::..:.:
plant   433 FGGGRRMCPAVYMGTTMVEFGL----ANLLYHFDWKLPEGMKVDDIDMEEAPGLTVNKKNELILV 493

  Fly   518 KRRPLGP 524
            ..:.|.|
plant   494 PTKFLDP 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	123/487 (25%)
CYP71B34	NP_189261.1	p450	7..498	CDD:299894	129/517 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910