DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B22

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189251.1	Gene:	CYP71B22 / 822221	AraportID:	AT3G26200	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	137/537 - (25%)
Similarity:	226/537 - (42%)	Gaps:	77/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MVFLGLLALVTLLQWLVRNYRELR----KLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLF 88
            :.||.||.|..:.      :::|.    ||||||.|||:||.|..:|...|..|.:|::.||.:.
plant     5 LYFLLLLPLFLIF------FKKLSPSKGKLPPGPLGLPIIGNLHQLGKSLHRSFHKLSQNYGPVM 63

  Fly    89 STRLGSQLTVVMSDYKMIRECFRRE--EFTGRP-------------DTPFMQTLNGYGIINSTGK 138
            ....|....||:|..:...|..:..  |...||             |..|.|          .|.
plant    64 FLHFGVVPVVVVSTREAAEEVLKTHDLETCTRPKLTATKLFSYNYKDIGFAQ----------YGD 118

  Fly   139 LWKDQRR------FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQP---VDMSPV 194
            .|::.|:      |...||:.|             :.|..|..|.:.:..:...:.   ||:...
plant   119 DWREMRKLAMLELFSSKKLKAF-------------RYIREEESEVLVNKLSKSAETRTMVDLRKA 170

  Fly   195 ISVAVSNVICSLMMSTRF-SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPT--MQCFPSISTAKN 256
            :....::::|.|.....| ..|.....:...|:.|.....|.....|:.|.  ......||...:
plant   171 LFSYTASIVCRLAFGQNFHECDFVDMDKVEDLVLESETNLGSFAFTDFFPAGLGWVIDRISGQHS 235

  Fly   257 KIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQV 321
            ::.:..|.:..|:|.|||||.:.....:..|::...|..|.|....|:....:|      .|..|
plant   236 ELHKAFARLSNFFQHVIDDHLKPGQSQDHSDIIGVMLDMINKESKVGSFQVTYD------HLKGV 294

  Fly   322 IIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP-TIEDLQYLPITESTILE 385
            :.|:|.||:.....|::|....:.|:|:.|:::|.|:.:::|.::.. |.:||:.:...:..|.|
plant   295 MSDVFLAGVNAGAITMIWAMTELARHPRVMKKLQQEIREILGDNKEKITEQDLEKVHYLKLVIEE 359

  Fly   386 SMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKV 450
            :.|.....||........|:::.||.||..:.:.....|:..|||.||.|.:|.|.||||:..:.
plant   360 TFRLHPPAPLLLPRETMSDLKIQGYNIPKNTMIEINTYSIGRDPNCWENPNDFNPERFIDSPVEY 424

  Fly   451 RKPEY-FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSL-KGNVGATITPESF 513
            :...| .:|||.|||:|.|.......:.|...:.::.||.:||:|..:..: ....||.:..:
plant   425 KGQHYELLPFGAGRRICPGMATGITIVELGLLNVLYFFDWSLPDGMKIEDIDMEEAGAFVVAK-- 487

  Fly   514 KVCLKRRPLGPTAADPH 530
            ||.|:   |.||   ||
plant   488 KVPLE---LIPT---PH 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	123/492 (25%)
CYP71B22	NP_189251.1	CYP71-like	59..491	CDD:410695	109/462 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900