DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B20

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189249.1	Gene:	CYP71B20 / 822219	AraportID:	AT3G26180	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	135/533 - (25%)
Similarity:	219/533 - (41%)	Gaps:	91/533 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LLALVTLLQWLVRNYRELR-KLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQL 96
            |:.|.:|: :..:..:.|: .|||.|...||||.|..:|...|.....||::||.:.....|...
plant    10 LITLASLI-FFAKKIKHLKWNLPPSPPKFPVIGNLHQIGELPHRSLQHLAERYGPVMLLHFGFVP 73

  Fly    97 TVVMSDYKMIRECFRREEF--TGRPD----------------TPFMQTLNGYGIINSTGKLWKDQ 143
            ..|:|..:...|..|..:.  ..||.                ||:             |..||.:
plant    74 VTVVSSREAAEEVLRTHDLDCCSRPKLVGTRLLSRNFKDVCFTPY-------------GNEWKAR 125

  Fly   144 RRFLHDKLRQ-FGMTYMGNGKQQMQKRIMTEVHEF-IGHLHAS--DGQPVDMSPVISVAVSNVIC 204
            |:|   .||: |.:.     |.|..:.|..|...| :..|..|  :..|||:|..:....:::..
plant   126 RKF---ALRELFCLK-----KVQSFRHIREEECNFLVKQLSESAVNRSPVDLSKSLFWLTASIFF 182

  Fly   205 SLMMSTRFS----IDDPKFRRFNFLIEEGMRLFGEIHTVDYIPT------MQCFPSISTAKNKIA 259
            .:.:...|.    ||..|.....|..|..:..|   ...|:.|.      :..|.......|.:.
plant   183 RVALGQNFHESNFIDKEKIEELVFEAETALASF---TCSDFFPVAGLGWLVDWFSGQHKRLNDVF 244

  Fly   260 QNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIID 324
            .   ::...:|.|||||..........|::|..|..|.|   ||.|:.|           ::|||
plant   245 Y---KLDALFQHVIDDHLNPGRSKEHEDIIDSMLDAIHK---EGKDSSL-----------ELIID 292

  Fly   325 --------LFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP-TIEDLQYLPITE 380
                    :|.||::|...|::|....:::|||.:::||.|:.:.:|.::.. |.||:..:|..:
plant   293 HIKGFLANIFLAGIDTGALTMIWAMTELVKNPKLIKKVQGEIREQLGSNKARITEEDIDKVPYLK 357

  Fly   381 STILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFID 445
            ..|.|:.|.....||.........:::.||.||....::..::::..||.||..||||.|.||:|
plant   358 MVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSAIGRDPKLWTNPEEFDPERFMD 422

  Fly   446 TEGKVRKPEY-FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATIT 509
            :....|...| .:|||.|||:|.|..:....:.|...:.::.||..||:|.....:......|:|
plant   423 SSVDYRGQHYELLPFGSGRRICPGMPMGIAAVELGLLNLLYFFDWKLPDGMTHKDIDTEEAGTLT 487

  Fly   510 PESFKVCLKRRPL 522
                  .:|:.||
plant   488 ------IVKKVPL 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	127/504 (25%)
CYP71B20	NP_189249.1	p450	30..499	CDD:299894	131/512 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900