DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B19

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189248.1	Gene:	CYP71B19 / 822218	AraportID:	AT3G26170	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	138/518 - (26%)
Similarity:	227/518 - (43%)	Gaps:	46/518 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTR 91
            |.||  |:..|:|:.:..:..|....|||.|...||||.|..:|...|.....||::||.:....
plant     6 LCVF--LITFVSLIFFAKKIKRSKWNLPPSPPKFPVIGNLHQIGELPHRSLQHLAERYGPVMLLH 68

  Fly    92 LGSQLTVVMSDYKMIRECFRREEF--TGRPDTPFMQTLN-GYGIINST--GKLWKDQRRFLHDKL 151
            .|.....|:|..:...|..|..:.  ..||.....:.|: .:..|..|  |..||.:|:|   .|
plant    69 FGFVPITVVSSREAAEEVLRTHDLDCCSRPKLVGTRLLSRDFKDIGFTPYGNEWKARRKF---AL 130

  Fly   152 RQ-FGMTYMGNGKQQMQKRIMTEVHEF-IGHLHAS--DGQPVDMSPVISVAVSNVICSLMMSTRF 212
            |: |.:.     |.|..:.|..|...| :..|..|  |..|||:|..:....::::..:.:...|
plant   131 RELFCLK-----KVQSFRHIREEECNFLVKQLSESAVDRSPVDLSKSLFWLTASILFRVALGQNF 190

  Fly   213 S----IDDPKFRRFNFLIEEGMRLFGEIHTVDYIPT------MQCFPSISTAKNKIAQNRAEMQR 267
            .    ||..|.....|..|..:..|   ...|:.|.      :..|.......|.:..   ::..
plant   191 HESDFIDKEKIEELVFEAETALASF---TCSDFFPVAGLGWLVDWFSGQHKRLNDVFY---KLDA 249

  Fly   268 FYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMET 332
            .:|.|||||..........|::|..|..|.|   :|.|:.|....:|   :...:.::|.||::|
plant   250 LFQHVIDDHLNPGRSKEHEDIIDSMLDVIHK---QGEDSSLELTIDH---IKGFLANIFLAGIDT 308

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVG--RHRLPTIEDLQYLPITESTILESMRRSSIVPL 395
            ...|::|....:::|||.:::||.::.:.:|  :.|: |.||::.:|..:..|.|:.|.....||
plant   309 GAITMIWAVTELVKNPKLIKKVQGDIREQLGSNKERI-TEEDIEKVPYLKMVIKETFRLHPAAPL 372

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPF 459
            .........:::.||.||....::..::::..||.||..|:||.|.||:|:....|...| .:||
plant   373 ILPRETMAHIKVQGYDIPPKRRILVNVSAIGRDPKLWTNPKEFDPERFMDSFVDYRGQHYELLPF 437

  Fly   460 GVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPL 522
            |.|||:|.|..:....:.|...:.::.||..||:|.....:......|:|... ||.||..|:
plant   438 GSGRRICPGMPMGIAAVELGLLNLLYFFDWKLPDGMTHKDIDTEEAGTLTIVK-KVPLKLVPV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	127/484 (26%)
CYP71B19	NP_189248.1	p450	25..499	CDD:299894	131/495 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900