DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B17

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_189247.1	Gene:	CYP71B17 / 822216	AraportID:	AT3G26160	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	145/518 - (27%)
Similarity:	227/518 - (43%)	Gaps:	44/518 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            ||.:||.....:|::...::  |.:..|||.|..|||||.|..:|...|..|..||::.|.:...
plant     5 LLCLFLITFVSLTIVGCKIK--RSIWNLPPSPPKLPVIGNLHQVGELPHRSFRRLAERTGHVMLL 67

  Fly    91 RLGSQLTVVMSDYKMIRECFRREEF--TGRPDTPFMQTLN-GYGIINST--GKLWKDQRRFL--- 147
            .||.....|:|..:...|..|..:.  ..||:....:.:: |:..:|.|  |:.||::||||
plant    68 HLGFVPVTVISSREAAEEVLRTHDLDCCSRPNLVGSRLISRGFKDLNFTPYGEEWKERRRFLVGE 132

  Fly   148 ---HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMS 209
               ..||:.|  .|:...:.....:.::|        .|.|..|||:|..:....::::..:...
plant   133 LFCSKKLQSF--IYIKEVECNFLVKKLSE--------SAVDQSPVDLSKTLFWLAASILFRVAFG 187

  Fly   210 TRFS----IDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTM---QCFPSISTAKNKIAQNRAEMQR 267
            ..|.    .|..|.....|..|...   |.....|:.|..   .....||....::.....::..
plant   188 QSFHESEFTDTDKIDELVFETETAQ---GSFTCSDFFPIAGLGWLVDWISGQHKRLNDVFLKLDA 249

  Fly   268 FYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMET 332
            ..|.|||||.......:.:|:||..|..:.|   :|.|..|....:|.:.|:..||   .||::|
plant   250 LLQHVIDDHSNPGRSKDHKDIVDVMLDVMHK---QGKDDSLRLTIDHIKGLLTNII---IAGIDT 308

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVG--RHRLPTIEDLQYLPITESTILESMRRSSIVPL 395
            ...|::|....:.|||:.|::||.|:...:|  |.|: |.|||..:|.....|.|:.|...:.||
plant   309 GALTMIWTMTELARNPEIMKKVQGEIRDRLGNNRERI-TKEDLDKVPFLNLVIKETFRLHPVAPL 372

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPF 459
            .........|::.||.||....::....::..||.||..||||:|.||||:....|...: .:||
plant   373 LLPRETMAHVKVQGYDIPPKRRILVNAWAIGRDPKLWTDPEEFKPERFIDSPVDYRGQHFELLPF 437

  Fly   460 GVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPL 522
            |.|||:|.|..:....|.|...:.::.||..||:|.....:......|:|... ||.||..|:
plant   438 GSGRRICPGMAMGMATLELGLLNLLYFFDWKLPDGMSHKDIDTEEAGTLTVVK-KVHLKLVPV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	135/483 (28%)
CYP71B17	NP_189247.1	p450	30..499	CDD:299894	138/489 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900