DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP76C1

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_850439.1	Gene:	CYP76C1 / 819164	AraportID:	AT2G45560	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	140/500 - (28%)
Similarity:	240/500 - (48%)	Gaps:	57/500 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QHLLMVFLGLLALVTLLQWLVRNYRELR---KLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYG 85
            |.||::|..:|:.. |:....|:.|..|   .|||||..||:||.:..:|...|..|.||:|.||
plant     7 QALLLLFCFILSCF-LIFTTTRSGRISRGATALPPGPPRLPIIGNIHLVGKHPHRSFAELSKTYG 70

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTLNGYGI----INSTGKLWKDQR 144
            .:.|.:|||..|||::..:..||..|..:  .:.|..|..::::|....    :.|:...|:
plant    71 PVMSLKLGSLNTVVIASPEAAREVLRTHDQILSARSPTNAVRSINHQDASLVWLPSSSARWR--- 132

  Fly   145 RFLHDKLRQFGMTYMGNGKQ-QMQKRI-MTEVHEFIGHLHASDG--QPVDMSPVISVAVSNVICS 205
                 .||:..:|.:.:.:: :..|.: |.:|.|.:..:..|..  :.||:|.|..:...|:|.:
plant   133 -----LLRRLSVTQLLSPQRIEATKALRMNKVKELVSFISESSDREESVDISRVAFITTLNIISN 192

  Fly   206 LMMSTRFSIDDPKFR---RFNFLIEEGMRLFGEIHTVD---YIPTMQCFPSISTAKN-KIAQNRA 263
            ::    ||:|...:.   ..|.:.:..:.:.....|.|   |.|.::........|. |:...|
plant   193 IL----FSVDLGSYNAKASINGVQDTVISVMDAAGTPDAANYFPFLRFLDLQGNVKTFKVCTER- 252

  Fly   264 EMQRFYQDVID---DHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQL-----VQ 320
             :.|.::..||   ..|.|  .||.:|:          :|.:..| .|.|.|..|.:|     ..
plant   253 -LVRVFRGFIDAKIAEKSS--QNNPKDV----------SKNDFVD-NLLDYKGDESELSISDIEH 303

  Fly   321 VIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILE 385
            :::|:|:||.:|..:||.|....:|:|||.|.:.|.|:|.|:|::.:....|:..||..::.:.|
plant   304 LLLDMFTAGTDTSSSTLEWAMTELLKNPKTMAKAQAEIDCVIGQNGIVEESDISKLPYLQAVVKE 368

  Fly   386 SMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKV 450
            :.|..:.|||........|.|:.|:.:...:.|:..:.::..||::|:.|.:|.|.||:..:..|
plant   369 TFRLHTPVPLLIPRKAESDAEILGFMVLKDTQVLVNVWAIGRDPSVWDNPSQFEPERFLGKDMDV 433

  Fly   451 RKPEY-FIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG 494
            |..:| ..|||.|||:|.|..||...:.|..||.::.||..||:|
plant   434 RGRDYELTPFGAGRRICPGMPLAMKTVSLMLASLLYSFDWKLPKG 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	129/466 (28%)
CYP76C1	NP_850439.1	p450	11..505	CDD:386267	136/495 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910