DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp18a1 and CYP71B6

DIOPT Version :9

Sequence 1:	NP_523403.2	Gene:	Cyp18a1 / 32858	FlyBaseID:	FBgn0010383	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_179995.1	Gene:	CYP71B6 / 816952	AraportID:	AT2G24180	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	125/493 - (25%)
Similarity:	227/493 - (46%)	Gaps:	39/493 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTR 91
            |:.:|.||.:..||.:.:  .|..:.|||||..||::|.:..:||..|....:|:.:||.:.:..
plant    12 LLPWLLLLLIPPLLIFFL--LRSPKNLPPGPPRLPILGNIHQLGSLPHRSLRDLSLKYGPVITVY 74

  Fly    92 LGSQLTVVMSDYKMIRECFR--REEFTGRPDTPFMQTL--NGYGI-INSTGKLWKDQRRFLHDKL 151
            |||..|||:...:...|..:  ..|...||.....::.  :|.|: ....|..::|.|:..  .|
plant    75 LGSVRTVVVHSPETAEEVLKLHDSECCTRPKLSITKSFFYDGLGLGFTKWGDYYRDVRKLC--VL 137

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            ..|.:....:.:...::.:...|:.|..  .||.|..||::..::..|::..|.:.....|....
plant   138 ELFSVKRANSFRNIREEELSRLVNSFSD--SASSGSSVDLTANLAKFVASFTCRMAFGLSFQGSG 200

  Fly   217 PKFRRFNFLIEEGMRLFGEIHTVDYIP----TMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHK 277
            .....|..|..|..|:.|:....|..|    .:.....:.:::.|..|   ::..|||..|.||:
plant   201 MDNETFLELFTEANRVIGKFAAADIFPGFGWILDRISGLDSSRRKSFQ---DLDTFYQKAIVDHR 262

  Fly   278 RSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINV 342
            ......:..||:|..|      |.:..:.:|...:..:..:..:|:|||.||::|...||.|...
plant   263 EKKKTEDREDLIDVLL------KLQSQETKLGSSRITDTHIRAIIMDLFVAGVDTSVITLDWTMA 321

  Fly   343 FMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVEL 407
            .:.|:|:.|::||.|:.:.||...:.|.:||:.|...:..|.|:.|..:..|:........:.::
plant   322 ELSRHPRVMKKVQAEIREHVGDKGIVTYDDLEALVYMKMVIKETWRLHAPSPILIPREAMTNFKI 386

  Fly   408 NGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEY-FIPFGVGRRMC----L 467
            .||.|..|:.:.....::..:|::|:.|:||.|.||:|:..:.:...: .:|||.|||.|    :
plant   387 KGYDIYPGTRIHVNAWAIGRNPDVWKDPDEFIPERFVDSNVETKGTSFELLPFGSGRRGCPAMYV 451

  Fly   468 GDVLARMELFLFFASFMHCFD------IALPEGQPLPS 499
            |  |:.:|..|  |:.::.||      :::.|...|.|
plant   452 G--LSTVEYTL--ANLLYHFDWKATEEVSVEEAPGLTS 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	117/466 (25%)
CYP71B6	NP_179995.1	p450	36..499	CDD:299894	118/467 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000