Protein Alignment Cyp18a1 and Cyp2j9

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_083255.1
• Gene: Cyp2j9 / 74519
• MGIID: 1921769
• Length: 502
• Species: Mus musculus
• Alignment Length: 507
• Identity: 166/507 - (32%)
• Similarity: 265/507 - (52%)
• Gaps: 37/507 - (7%)

  Fly    23 AQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG-SEKHTRFMELAKQYGS 86
            |.||.::.|..:..:.|..:| :| |..:..||||..||.:|.|..:. .:.|....:..|:||:
Mouse    15 ALHLRILLLSAVTFLFLADFL-KN-RRPKNYPPGPMRLPFVGCLFHLDPKQPHLSLQQFVKKYGN 77

  Fly    87 LFSTRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLH 148
            :.|....:..:||::...:|:|.|.:.|  |..||.|...:.| |..|:|.|:.:.||:||||..
Mouse    78 VLSLDFANIPSVVITGMPLIKEIFTQMEHNFMNRPVTLLRKHLFNKNGLIFSSDQTWKEQRRFAL 142

  Fly   149 DKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFS 213
            ..||.||:     ||:.:::||..|.|..:..:....|||.|....||.||||:|||:....||.
Mouse   143 MTLRNFGL-----GKRSLEERIQEEAHYLVEAIRDEGGQPFDPHFNISNAVSNIICSITFGERFD 202

  Fly   214 IDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQC-----FPSI----STAKNKIAQNRAEMQRFY 269
            ..|.:|:....|::|.|.|..         :|.|     ||.|    ..:...:.:|..::|.|.
Mouse   203 YHDSQFQEMLRLLDEAMCLES---------SMMCQLYNIFPRILQYLPGSHQTLFRNWRKLQLFV 258

  Fly   270 QDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIK 334
            .|::::|:|.:||:..||.:|.:|.|:.|...:.|.:      .:||.|:...:|||.||.||..
Mouse   259 SDIVNNHRRDWDPDEPRDFIDAFLTEMTKYPDKTTTS------FNEENLICSTLDLFFAGTETTS 317

  Fly   335 TTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTH 399
            |||.|..:.|...|:...::|.|:|:|:|:.|.|.:.|...:|.|.:.|.|..|..:|:|.....
Mouse   318 TTLRWALLCMALYPEVQEKMQAEIDRVIGQARQPNLADRDSMPYTNAVIHEVQRMGNIIPFNVPR 382

  Fly   400 SPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRR 464
            ....|.:|.|:.:|.|..|:..:.::|.||:.|..|:.|.|..|:: .|:.:|.|.|:||.:|:|
Mouse   383 EVAVDTQLAGFNLPKGIMVLSNLTALHRDPSEWTTPDTFNPEHFLE-NGQFKKRESFLPFSMGKR 446

  Fly   465 MCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            .|||:.|||.|||:|..:....|....|..:.| ||:..:.||::|.|.::|
Mouse   447 ACLGEQLARSELFIFITTLFQKFTFKPPVNEKL-SLQFRMAATVSPVSHRLC 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	158/476 (33%)
Cyp2j9	NP_083255.1	p450	44..497	CDD:278495	157/474 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	290	1.000	Domainoid score	I1539
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm43796
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.720