Protein Alignment Cyp18a1 and Cyp2c55

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_082365.1
• Gene: Cyp2c55 / 72082
• MGIID: 1919332
• Length: 490
• Species: Mus musculus
• Alignment Length: 481
• Identity: 153/481 - (31%)
• Similarity: 251/481 - (52%)
• Gaps: 43/481 - (8%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR-FMELAKQYGSLFS 89
            :|::.|.|..|:.|..|...:.|  .||||||...|:||.:|.:..:..:: |...:|.||.:|:
Mouse     4 VLVLVLTLSCLLLLSLWRQNSGR--GKLPPGPTPFPIIGNILQIDIKNISKSFNYFSKVYGPVFT 66

  Fly    90 TRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNG-YGIINSTGKLWKDQRRFLHDKL 151
            ...||:.|||:..|:.::|..  ..|||:||......:.:|. .|:|.|.|..||:.|||....|
Mouse    67 LYFGSKPTVVVHGYEAVKEALDDLGEEFSGRGSFQIFERINNDLGVIFSNGTKWKELRRFSIMTL 131

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            |.|||     ||:.::.||..|....:..|..::|...|.:.::|.|.||||||::...||...|
Mouse   132 RSFGM-----GKRSIEDRIQEEASCLVEELRKANGSLCDPTFILSCAPSNVICSVIFHNRFDYKD 191

  Fly   217 PKF--------RRFNFLIEEGMRLFGEIHT-VDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDV 272
            .||        ..|..|....|:::..:.| ::|:|         .:.||:.:|..|::.:....
Mouse   192 EKFLNLMERLNENFKILNSPWMQVYNALPTLINYLP---------GSHNKVIKNFTEIKSYILGR 247

  Fly   273 IDDHKRSFDPNNIRDLVDFYLCEIEKAK----AEGTDAELFDGKNHEEQLVQVIIDLFSAGMETI 333
            :.:|:.:.|.:|.||.:|.:|.::|:.|    :|.|          .|.|:..:.|:|.||.||.
Mouse   248 VKEHQETLDMDNPRDFIDCFLIKMEQEKHNPHSEFT----------IESLMATVTDIFVAGTETT 302

  Fly   334 KTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            ..||.:..:.:|::.:...:||.|:|.|:||||.|.::|...:|.|::.:.|..|...::|....
Mouse   303 NITLRYGLLLLLKHTEVTAKVQAEIDHVIGRHRSPCMQDRTRMPYTDAMVHEIQRYIDLIPNNVP 367

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGR 463
            |:.|.:|....|.||.|:.::..:.||..|...:..||.|.|..|:|..|..:|.:||:||.:|:
Mouse   368 HAATCNVRFRSYFIPKGTELVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSIGK 432

  Fly   464 RMCLGDVLARMELFLFFASFMHCFDI 489
            |||:|:.|||.||||...:.:..|::
Mouse   433 RMCVGEALARTELFLILTTILQNFNL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	144/453 (32%)
Cyp2c55	NP_082365.1	p450	30..485	CDD:278495	144/453 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820