Protein Alignment Cyp18a1 and Cyp2ab1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_017453675.1
• Gene: Cyp2ab1 / 679979
• RGDID: 1586963
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 147/449 - (32%)
• Similarity: 222/449 - (49%)
• Gaps: 31/449 - (6%)

  Fly    79 ELAKQYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNG-YGIINSTGKLW 140
            :||:.:|::|:..|||...||::.::.::|..  ..|:|:|||.|||.:.|.| .|:|.|.|..|
  Rat    53 QLAQTHGNVFTVWLGSTPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTW 117

  Fly   141 KDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICS 205
            :.||||....||:.|:     |||.::.::..|..|.....|...|:..|....|..:.:.||.:
  Rat   118 RQQRRFCLTTLRELGL-----GKQALELQLQHEAAELAEVFHQEQGRAFDPQVPIIRSTTRVIGA 177

  Fly   206 LMMSTRFSIDDPKFRRFNFLIEEGM--------RLFGEIHTVDYIPTMQCFPSISTAKNKIAQNR 262
            |:....|..::|.|......|..|:        ||:      |..|....:  :|....||.|..
  Rat   178 LVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLY------DMFPWALRY--LSGPHQKIFQYH 234

  Fly   263 AEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFS 327
            ..::.|....|..||.. .|...:|.:..||.:|.||..:  ....|.    ||.|:||:||||.
  Rat   235 EAVRGFIHHEIIRHKLR-TPEAPKDFISCYLSQITKAMDD--PVSTFS----EENLIQVVIDLFL 292

  Fly   328 AGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSI 392
            .|.:|..|||.|..::::.:.....|||.|||:|:|..:....||.:.||.|.:.:.|..|.||:
  Rat   293 GGTDTTATTLHWAIIYLVHHRAIQERVQQELDEVLGTAQAVCYEDRERLPYTRAVLHEVQRLSSV 357

  Fly   393 VPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFI 457
            |.:...........::||.:..|:.::|.:.||..||..||.|.:|.|..|:|.:|.....|.|:
  Rat   358 VAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFL 422

  Fly   458 PFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            ||..|.|:|.|:.||||||||.||:.:..|...||||.....|:...|.|:.|:..|:|
  Rat   423 PFSAGHRVCPGEQLARMELFLMFATLLRTFRFQLPEGSQGLRLEYVFGGTLQPQPQKIC 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	143/440 (33%)
Cyp2ab1	XP_017453675.1	CYP2AB1-like	58..480	CDD:410760	143/441 (32%)