Protein Alignment Cyp18a1 and cyp2r1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001373291.1
• Gene: cyp2r1 / 563369
• ZFINID: ZDB-GENE-110114-1
• Length: 506
• Species: Danio rerio
• Alignment Length: 501
• Identity: 163/501 - (32%)
• Similarity: 254/501 - (50%)
• Gaps: 24/501 - (4%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            ||.:|..||.|:.:.| ||:. |..|..||||..||:||.:|.:.:|.|......:..:|.:||.
Zfish    22 LLGLFTTLLILLVIRQ-LVKQ-RRPRGFPPGPTPLPIIGNMLSLATEPHVYMKRQSDIHGQIFSL 84

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNGY-GIIN-STGKLWKDQRRFLHDKL 151
            .||...||:::.|..|:||.  :.|.|..||..|..|.:... |::| ..|:.|.:     |.||
Zfish    85 DLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTKMGGLLNCKYGRGWIE-----HHKL 144

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            ......|.|.| |:|.:||..|...|:..:....|:|.:...:::.||||:...::...||:.||
Zfish   145 AVNCFRYFGTG-QRMFERISEECLYFLDAIDQHQGKPFNPKHLVTNAVSNITNLIIFGQRFTYDD 208

  Fly   217 PKFRRFNFLIEEGMRLFGEIHTVDY--IPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRS 279
            ..|:....:..|.:.|........|  .|.|:..|  .....::.:|..|:.:|...:|....:.
Zfish   209 GDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLP--FGKHQRLFRNANEVYKFLLQIIRRFSQG 271

  Fly   280 FDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFM 344
            ..|.:.:..:|.||.|:|::..:  .|..|.    ::.|:..:.:|..||.||....|.|..::|
Zfish   272 RVPQSPQHYIDAYLDEMEQSTPD--KATSFS----QDNLIFSVGELIIAGTETTTNCLRWAMLYM 330

  Fly   345 LRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNG 409
            ...|:...:||.|:|.|: ..|.|..||.|.:|..|:.:.|.:|..:||||....:.::|..:.|
Zfish   331 ALYPRIQEKVQMEIDSVL-NGRQPAFEDRQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRG 394

  Fly   410 YTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARM 474
            ||||.|:.||..:.|||.|...|..|..|.|.||:|..||..:.|.|:||.:|:|.|||:.|||:
Zfish   395 YTIPKGTMVITNLYSVHFDEKYWSDPSIFCPERFLDCNGKFIRHEAFLPFSIGKRHCLGEQLARL 459

  Fly   475 ELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            |:||||.:.:..|.:...||. :|||...:|.|:.|:.:.:|..||
Zfish   460 EMFLFFTTLLQRFHLQFSEGF-IPSLSAKLGMTLQPQPYSICAIRR 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	138/435 (32%)
cyp2r1	NP_001373291.1	CYP2R1	67..500	CDD:410754	139/448 (31%)