Protein Alignment Cyp18a1 and cyp2a6.7

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_002939424.3
• Gene: cyp2a6.7 / 548374
• XenbaseID: XB-GENE-5764740
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 167/514 - (32%)
• Similarity: 258/514 - (50%)
• Gaps: 59/514 - (11%)

  Fly    31 LGLLALVTLLQWLV------RNYRELRKLPPGPWGLPVIGYLL-FMGSEKHTRFMELAKQYGSLF 88
            ||.|.|:.|:..:|      ..||: |.|||||..||:||.|| ....|......|..||||.::
 Frog     6 LGTLVLILLISCIVIYSTWNSMYRK-RNLPPGPTPLPLIGNLLQIKRGEMVKSLTEFGKQYGPVY 69

  Fly    89 STRLGSQLTVVMSDYKMIRECF--RREEFTGR-----PDTPFMQTLNGYGIINSTGKLWKDQRRF 146
            :..||.:..:|::.|:.::|..  :.|||:||     .|..|    .|:|::.|.|..||..|||
 Frog    70 TLYLGPRPVIVLNGYQAVKEALIDQGEEFSGRGKLVVADLIF----GGFGVVFSNGDRWKQLRRF 130

  Fly   147 LHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTR 211
            ....||.|||     ||:.:::||..|.......||.....|.|...::..||||||||::...|
 Frog   131 SLMTLRDFGM-----GKRSIEERIKEEAQCLQVELHKYKQTPTDPQNILVQAVSNVICSVVFGNR 190

  Fly   212 FSIDDPKF----RRFNFLIEEGMRLFGEIHTV-----DYIPTMQCFPSISTAKNKIAQNRAEMQR 267
            |..::.:|    |.||...:.....:|::..:     :|||         ....||.:..|....
 Frog   191 FEYENSEFLKLLRLFNETFQMMSSTWGQLQQIIPFIMNYIP---------GPHQKIDKVVARQLE 246

  Fly   268 FYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMET 332
            |..:.:..::.:.|.|:.||.:|.:|.::::.....|..  |:.||    |:..:::||.||.||
 Frog   247 FVSERVKKNQETIDFNSPRDFIDCFLIKMQQETQNPTSE--FNLKN----LLMTVLNLFVAGTET 305

  Fly   333 IKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLAT 397
            :.:||....:.:|:.|....::..|:|.|:|::|.|.|:|...:|..::.|.|..|.:.|:|:..
 Frog   306 VSSTLRNGILLLLKYPHIQEKLHKEIDVVIGQNRSPNIDDRSKMPYMDAVIHEIQRFTDILPMNL 370

  Fly   398 THSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVG 462
            .||..:|....|||||..:.|.|::.||..||..:..||.|.|..|:|..|..:|.:.|:||..|
 Frog   371 PHSVIKDTAFQGYTIPKDTDVYPMLCSVLRDPTQFTTPENFNPEHFLDDSGCFKKSDAFMPFSTG 435

  Fly   463 RRMCLGDVLARMELFLFFASFMHCFDIA----LPEGQPLPSLKG--NVGATITPESFKV 515
            :|:|||:.|||||||||..:.:..|.:.    :.|....|.:.|  ||     |.|:||
 Frog   436 KRICLGEGLARMELFLFLTTILQNFTLTSETQITESDITPRMAGFANV-----PISYKV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	157/485 (32%)
cyp2a6.7	XP_002939424.3	CYP2	65..489	CDD:410652	141/452 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970