Protein Alignment Cyp18a1 and Cyp2c24

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001258283.1
• Gene: Cyp2c24 / 499353
• RGDID: 1563697
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 163/520 - (31%)
• Similarity: 263/520 - (50%)
• Gaps: 66/520 - (12%)

  Fly    26 LLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR-FMELAKQYGSLFS 89
            :|::.|.|..|:.|..|  |......||||||..||:||.:|.:..:..:: |...:|.||.:|:
  Rat     4 VLVLVLTLSCLLLLSLW--RQSSGRGKLPPGPTPLPIIGNILQIDVKDISKSFTNFSKIYGPVFT 66

  Fly    90 TRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKL 151
            ...|.:.|||:..|:.::|..  ..|||:||...|.::.: ||.|:|.|.|..||:.|.|....|
  Rat    67 LYFGPKPTVVVHGYEAVKEALDDLGEEFSGRGSFPIVERMNNGLGVIFSNGTKWKELRHFSLMTL 131

  Fly   152 RQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDD 216
            |.|||     ||:.::.||..|....:..|..::|...|.:.::|.|.||||||::...||...|
  Rat   132 RNFGM-----GKRSIEDRIQEEASCLVEELRKTNGSLCDPTFILSCAPSNVICSVVFHNRFDYKD 191

  Fly   217 PKF--------RRFNFLIEEGMRLFGEIHT-VDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDV 272
            ..|        ..|..|....|::...:.. :||:|         .:.|::.:|.||::.:....
  Rat   192 ENFLNLMEKLNENFKILNSPWMQVCNALPAFIDYLP---------GSHNRVIKNFAEIKSYILRR 247

  Fly   273 IDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHE-------EQLVQVIIDLFSAGM 330
            :.:|:.:.|.:|.||.:|.:|.::|:.|             |.       |.|:..:.|:|.||.
  Rat   248 VKEHQETLDMDNPRDFIDCFLIKMEQEK-------------HNPRTEFTIESLMATVSDVFVAGS 299

  Fly   331 ETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPL 395
            ||..|||.:..:.:|::.:...:||:|:|.|:||||.|.::|...:|.|::.:.|..|..:::|.
  Rat   300 ETTSTTLRYGLLLLLKHTEVTAKVQEEIDHVIGRHRRPCMQDRTRMPYTDAMVHEIQRYINLIPN 364

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFG 460
            ...|:.|.:|....|.||.|:.::..:.||..|...:..||.|.|..|:|..|..:|.:||:||.
  Rat   365 NVPHAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFS 429

  Fly   461 VGRRMCLGDVLARMELFLFFA---------SFMHCFDIALPEGQPLPSLKGNVGATITPESFKVC 516
            .|:|||:|:.||||||||...         ||:...||   :..|:.:..|.|     |.|:::|
  Rat   430 TGKRMCVGEALARMELFLLLTTIVQNFNLKSFVDTKDI---DTTPMANTFGRV-----PPSYQLC 486

  Fly   517  516
              Rat   487  486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	154/492 (31%)
Cyp2c24	NP_001258283.1	p450	30..487	CDD:278495	154/492 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820