Protein Alignment Cyp18a1 and cyp2a6.8

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001010999.1
• Gene: cyp2a6.8 / 496408
• XenbaseID: XB-GENE-5806705
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 160/494 - (32%)
• Similarity: 258/494 - (52%)
• Gaps: 41/494 - (8%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLL-FMGSEKHTRFMELAKQYGSLFST 90
            |.:|| |:|.:.:.....:.||: |.|||||..:|:.|.:| ....|.....:||.|:||.:::.
 Frog     9 LQLFL-LIATMLIYSTWNKMYRK-RNLPPGPTPIPLFGNVLQIKRGEMVKSLLELGKKYGPVYTL 71

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTP-FMQTLNGYGIINSTGKLWKDQRRFLHDKLR 152
            ..|....:::.||:.|:|..  :.|||:||...| :.|...|||...|.|..||..|||....||
 Frog    72 YFGPSPVIILCDYQSIKEALNDQAEEFSGRGKIPSWDQFFQGYGESFSNGDEWKQLRRFSLTTLR 136

  Fly   153 QFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDP 217
            .|||     ||:.:::||..|....:..:.:..|:|.|.:.::...|||||||::...|:...:.
 Frog   137 NFGM-----GKRGIEERIQEEAQFLVAEIKSYKGKPFDPTKILVQCVSNVICSVVFGQRYEYSNK 196

  Fly   218 KFRR----FNFLIEEGMRLFGEIHT-----VDYIPTMQCFPSISTAKNKIAQ-NRAEMQRFYQDV 272
            .|.:    |..:.|:.....|::.|     :::||...     .|..||:.: |...:||
 Frog   197 DFHKLLYMFQAVFEDTSSTLGQLMTLLPNIMNHIPGPH-----KTVVNKLNKVNDFILQR----- 251

  Fly   273 IDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTL 337
            :.:::::.|||:.|..:|.:|.:::|.|.....      |.|.:.|:..|::||.||.||:.|||
 Frog   252 VKENEKTLDPNSPRHFIDSFLIQMQKEKDNPVT------KFHWKNLLCTIMNLFFAGTETVSTTL 310

  Fly   338 LWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPT 402
            ....:.:|.:|:...::.:|:|:|||:.|.|||||...:|.|::.|.|..|.|.::|::..|...
 Frog   311 RHGFLMLLIHPEIEEKLHEEIDRVVGQDRSPTIEDRSKMPYTDAVIHEIQRFSDVLPMSLPHLVM 375

  Fly   403 RDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCL 467
            :|.:..|||||.|:.|.|||.:...||..:..|.:|.|..|:|..|..:....|:||..|:|:||
 Frog   376 KDTQFRGYTIPKGTDVYPLICAALRDPKQFATPNKFNPQHFLDDNGLFKSSNAFLPFSTGKRICL 440

  Fly   468 GDVLARMELFLFFASFMHCFDI----ALPEGQPLPSLKG 502
            |:.|||||||||..:.:..|.:    ...|....|.:.|
 Frog   441 GEGLARMELFLFLTNILQNFKLHSENQFAEDDIAPKMNG 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	151/467 (32%)
cyp2a6.8	NP_001010999.1	p450	34..489	CDD:365848	151/467 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970