Protein Alignment Cyp18a1 and Cyp303a1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 141/520 - (27%)
• Similarity: 237/520 - (45%)
• Gaps: 67/520 - (12%)

  Fly    38 TLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR---FMEL----AKQYGS---LFSTRL 92
            |||..|....|:.::.||||...|::|..|.: |:...|   |.::    |:||.:   .:..::
  Fly    12 TLLAILFGGVRKPKRFPPGPAWYPIVGSALQV-SQLRCRLGMFCKVIDVFARQYVNPYGFYGLKI 75

  Fly    93 GSQLTVVMSDYKMIRECFRREEFTGRPDTPF--MQTLNG-YGIINSTGKLWKDQRRFLHDKLRQF 154
            |....|:......|.|....|:..||||..|  ::|.|. .|::.:.|::|.:||||:...|:.|
  Fly    76 GKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNF 140

  Fly   155 GMTYMGNGKQQMQKRIMTEVH--------EFIGHLHASDGQP--VDMSPVISVAVSNVICSLMMS 209
            |....|         :|..||        :....:..|.|:.  ::|..:.||.|.|.:..::..
  Fly   141 GFARSG---------MMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSG 196

  Fly   210 TRFSIDDPKFRRFNFLIEEGMRLFGEIHTV----DYIPTMQCFPSISTAKNKIAQNRAEMQRFYQ 270
            .|:....|:..:   |:|....||..|..|    .:.|.::......:..|...::...:..|..
  Fly   197 RRYEPGSPEITQ---LLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMS 258

  Fly   271 DVIDDHKRSF----DPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGME 331
            ..|:.|:.::    :|   |||:|.||    :|:.||.|.:   |...::.|:.:.:|:|.||.|
  Fly   259 KEIELHRLTYKNYDEP---RDLMDSYL----RAQDEGNDEK---GMFSDQSLLAICLDMFLAGSE 313

  Fly   332 TIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPT-IEDLQYLPITESTILESMRRSSIVPL 395
            |...:|.:..:.::..|:...|...|:.:|||..|:|. ..|...||..|:..||::|...:...
  Fly   314 TTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTF 378

  Fly   396 ATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFG 460
            ...|....|..|:||.||..:.||.....:.::|..:..||.|.|.|:: .:|.::.||.|.|||
  Fly   379 GIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFG 442

  Fly   461 VGRRMCLGDVLARMELFLFFASFMHCFDIA-----LPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            .||..|:||:|.|..||:|..:.:..|.:.     :||..||.      |||...:.:.:.|..|
  Fly   443 FGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE------GATAAVKPYDIMLVAR 501

  Fly   521  520
              Fly   502  501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	121/459 (26%)
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	121/456 (27%)