Protein Alignment Cyp18a1 and Cyp304a1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_001237486.2
• Gene: Cyp304a1 / 4576991
• VectorBaseID: AGAMI1_012866
• Length: 553
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 152/548 - (27%)
• Similarity: 238/548 - (43%)
• Gaps: 78/548 - (14%)

  Fly    34 LALVTLLQW----LVRNYR-ELRKL------PPGPWG--LPVIGYLLFMGSEKHTRFMELAKQYG 85
            :.:::.|.|    |:.:|| .|.::      ||||..  .|:..|.|.: ...|......|.:..
Mosquito    30 MPVISALLWSAVVLLLSYRFYLNRIKRPLNYPPGPAVRLSPLQDYALLL-LLNHRHLQRAASRLA 93

  Fly    86 SLFSTR-LGSQL----TVVMSDYKMIRECFRREEFTGRPDTPFMQT-------LNGYGIINSTGK 138
            ..:.|: ||..|    ||::.|.::.|:...|.|..||||. |:..       |.|...|:..|
Mosquito    94 HFYRTKVLGLFLAGLPTVIVRDGEIARKLLTRRELDGRPDL-FLARMRQKEFHLRGINFIDGPG- 156

  Fly   139 LWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHAS-----------DGQPVDMS 192
             |||||.|....||.:|   .|...:|.::.:..|:.:.:|.|.:.           ||..|...
Mosquito   157 -WKDQRWFFLRHLRDYG---FGRRSEQYEQEMEKELWKLVGQLASGERYGYERDFMRDGGAVKCP 217

  Fly   193 PVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRL---------FGEIHTVDYIPTMQCF 248
            .|..|.::|:...:.:..|:..:     |...|:..|.:.         :|.|.|  |:|.::..
Mosquito   218 DVFLVTLANIFLQVTIGERYDRE-----RAKSLLVAGRKAMLFARNADDYGTIFT--YLPWLRFV 275

  Fly   249 PSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKN 313
            ...:...:.|......:.:..:.:||...::|||||.|..||.||.|::....:..:...
Mosquito   276 FPFTIKYSNIRSGMMGVNQLLETIIDKQLQAFDPNNPRHFVDVYLREMQNHVPQRNETTF----- 335

  Fly   314 HEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPI 378
            ..:|||..:.|.|..........|..:...:|.||..:||:|.|:|:||...||||:.|...||.
Mosquito   336 QYDQLVLGLADCFIPSTAGAAVQLSMLLERLLLNPTVVRRMQKEIDEVVDSDRLPTLNDRVNLPY 400

  Fly   379 TESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF 443
            ||:||.|.:|..:::|....|...:.:|..||:.|..:..:..::||:..|.:|..|..|||.|.
Mosquito   401 TEATIREGLRIDTLIPSGIVHRAQQTIEFEGYSAPENTLFLFDLDSVNNQPEVWGDPRTFRPDRM 465

  Fly   444 IDTE------GKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSL-K 501
            :|.|      .|.|.    :.|.||||.|.|....|..:||..|:.:..|::...:...||.| |
Mosquito   466 LDEETGMLALSKDRS----LTFSVGRRECPGQTYTRNVMFLIVATLVQRFELLPLQSDRLPDLSK 526

  Fly   502 GNVGATITPESFKV-CLKRRPLGPTAAD 528
            ...|....|:.|.| .|.||..|  |||
Mosquito   527 RQTGLVHGPDDFWVRFLPRRTSG--AAD 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	129/468 (28%)
Cyp304a1	XP_001237486.2	None