Protein Alignment Cyp18a1 and Cyp6a17

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 127/529 - (24%)
• Similarity: 224/529 - (42%)
• Gaps: 97/529 - (18%)

  Fly    28 MVFLGLLALV-TLLQWLVR---NYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQY---- 84
            |:.|.|:.:: :||.:..|   .|.:.|.:|..... |:.|.:....:::|  ..|:.:.|
  Fly     1 MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVH-PLFGNIKDWPNKRH--IAEIFRDYYFKY 62

  Fly    85 ---------GSLFSTRLGSQLTVVMSDYKMIRECF--------RREEFTGRPDTPFMQTLNGYGI 132
                     ...|.||     |.|::|.::::...        .|..|....|.|...||
  Fly    63 KNSDYPFAGFFFFFTR-----TAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATL----- 117

  Fly   133 INSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHE-----FIGHLHASDGQPVDMS 192
            .:..|:.|    |.|..||..   |:. :||.:....|:.:|.|     |.....|..||.:::.
  Fly   118 FSIEGQKW----RHLRHKLTP---TFT-SGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVV 174

  Fly   193 PVISVAVSNVI--CSLMMSTRFSIDDPKF------------RRFNFLIEEGMRLFGEIHTVDYIP 243
            .:::...::||  |:..::.. |:.|||.            .|:..:::  :.|||
  Fly   175 DLVARYTADVIGNCAFGLNCN-SLYDPKAEFVSIGKRAITEHRYGNMLD--IFLFG--------- 227

  Fly   244 TMQCFPSISTAKNKIAQNRAEMQRFY----QDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGT 304
                ||.:| .:.::..|..|.:.||    ::.||...|:.:..|  |.:| .|.|:.|.:..|.
  Fly   228 ----FPKLS-RRLRLKLNIQEAEDFYTKIVRETIDYRLRTKEKRN--DFMD-SLIEMYKNEQSGN 284

  Fly   305 DAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP- 368
            ..   ||....|.|.|..| .|.||.||..||:.:....:.||.....::::|:..|.|:|...
  Fly   285 SE---DGLTFNELLAQAFI-FFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEF 345

  Fly   369 TIEDLQYLPITESTILESMRRSSIVPLATTHSPTR-DVELNGYTIPAGSHVIPLINSVHMDPNLW 432
            |.|.::.:...|..::|::|:..::...|..:.|. ..|...|.|..|:.|:.....:|.||:::
  Fly   346 TYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIY 410

  Fly   433 EKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIAL-PEGQ- 495
            .:||.|:|.||.|.|...|....::|||.|.|.|:|.....|:..:..|..:..:..:: ||.|
  Fly   411 PEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQI 475

  Fly   496 PLPSLKGNV 504
            |:..:..|:
  Fly   476 PMKIVVKNI 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	113/455 (25%)
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	113/461 (25%)