Protein Alignment Cyp18a1 and cyp2c8.2

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001005711.1
• Gene: cyp2c8.2 / 448236
• XenbaseID: XB-GENE-5852312
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 162/479 - (33%)
• Similarity: 251/479 - (52%)
• Gaps: 41/479 - (8%)

  Fly    27 LMVFLGL-LALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFST 90
            |.:||.| :.|:.|..|  :.::...:|||||:.||::|.:|...:..:..:.:|::|||.:|:.
 Frog     4 LTIFLCLFIFLLLLFTW--KTHKRRVQLPPGPYPLPLLGNVLQGITVLYDSYRKLSEQYGPVFTV 66

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLR 152
            .|||...||:..|:::::..  ..:||..|...|..:.| :|||:|::.|..|:..|||....||
 Frog    67 WLGSTPMVVLCGYEVLKDALINHSQEFGARGAFPVPERLTDGYGVISTNGTRWQQLRRFSVTVLR 131

  Fly   153 QFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDP 217
            .|||     ||:.|::||..|....|..:..:.|:..|...::..||:|:|..::...|:...|.
 Frog   132 NFGM-----GKRSMEERIHEETQHLIQAVQHTGGEAFDPLYLLGRAVNNIINLIVFGRRWDYKDK 191

  Fly   218 -KFRRFNFLIEEGMRLF-----GEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDH 276
             ..:.||.:  ..:.||     |.|::..| ..||..|.   ...||..:...::.|.::.|:.|
 Frog   192 MMIKLFNII--NSILLFLRSPLGVIYSALY-QIMQHLPG---PHQKIFHDSETVKSFIREQINSH 250

  Fly   277 KRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNH------EEQLVQVIIDLFSAGMETIKT 335
            |.:.|.::.||.:|   |.:.||..|         |:|      :|.||..:.|.|.||.||...
 Frog   251 KETLDSDSPRDYID---CFLIKANQE---------KDHHSSEFSQENLVNTVFDFFVAGTETATN 303

  Fly   336 TLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHS 400
            |:.:..:.::..|....:||.|:|:|||..|||.|.|...:|.|.:.|.|..|...:|||:..|.
 Frog   304 TIQFSLLVIITYPHIQAQVQKEIDKVVGPDRLPGIADRAQMPYTNAVIHEIHRFLDLVPLSLPHM 368

  Fly   401 PTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRM 465
            .|:|....|:.||.|:.|||||.|...||..||.||||.|..|::..|:...|..|:||..|:|:
 Frog   369 ATQDTVCRGFRIPKGTTVIPLIGSALCDPAHWETPEEFNPEHFLNQNGEFYIPPAFMPFSAGKRV 433

  Fly   466 CLGDVLARMELFLFFASFMHCFDI 489
            |||:.|||||:||||.:.:..|.|
 Frog   434 CLGEGLARMEIFLFFTALLQKFTI 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	154/451 (34%)
cyp2c8.2	NP_001005711.1	p450	49..464	CDD:365848	146/432 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2625
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm48967
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050