Protein Alignment Cyp18a1 and Cyp304a1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 145/495 - (29%)
• Similarity: 234/495 - (47%)
• Gaps: 43/495 - (8%)

  Fly    54 PPGPWGLPVIGYLLFM----GSEKHTRFMELAKQYGS-LFSTRLGSQLTVVMSDYKMIRECFRRE 113
            ||||..:|:.|..|||    ....|...:.|::.|.| :....:|.....|:.....:||....:
  Fly    30 PPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQ 94

  Fly   114 EFTGRPDTPFMQTLNG-----YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTE 173
            .|.|||.. |:..:..     .||....|.|||:||||:...||.||   .|....|::..|..:
  Fly    95 VFDGRPQL-FVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFG---FGRRFDQLELVIQEQ 155

  Fly   174 VHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLI---EEG------ 229
            :::.:..:......|.:...|.|... .|:..|:.:. ||.:...:..:|..:   |.|
  Fly   156 LNDMLDLIRNGPKYPHEHEMVKSGGY-RVLLPLLFNP-FSANAHFYIVYNECLSREEMGKLVKLC 218

  Fly   230 -MRLFGEIHTVDYIPTMQCFPSIS------TAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRD 287
             |.:..:.:..||...:...|.|.      :..||:.::...:::|:.|.:|.:..|::....|:
  Fly   219 QMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVERN 283

  Fly   288 LVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMR 352
            .:|.|:.|:.:....|.         :.:||:..::|........|...|..:..:::..|..:|
  Fly   284 FMDVYIAEMRRGPGYGF---------NRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLR 339

  Fly   353 RVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSH 417
            |||:|:|:|||..|||.:||.:.||.||:||.|.:|..::||....|....|.||.||.||..:.
  Fly   340 RVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTI 404

  Fly   418 VIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKV-RKPEYFIPFGVGRRMCLGDVLARMELFLFFA 481
            |:|.:.:.|.|..:|..||:|||.||:|.:||: .|.:..:|||.|:|:|.|:..||..|||..|
  Fly   405 VVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTA 469

  Fly   482 SFMHCFDIALPEGQPLPSLKGNV-GATITPESFKVCLKRR 520
            :....||..|.....||.|..|: |..|:|..|.:.|:.|
  Fly   470 TMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	131/453 (29%)
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	131/452 (29%)