Protein Alignment Cyp18a1 and MGC69353

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001001212.1
• Gene: MGC69353 / 407870
• XenbaseID: XB-GENE-5744235
• Length: 496
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 163/481 - (33%)
• Similarity: 257/481 - (53%)
• Gaps: 38/481 - (7%)

  Fly    33 LLALVTLLQWLVRNYRELRK--LPPGPWGLPVIGYLLFMGS-EKHTRFMELAKQYGSLFSTRLGS 94
            ||.:..||..|.|...:..|  |||||..||::|.||.:.| |.|...:|..|:||.:::..:||
 Frog    13 LLLIAALLLLLARKVGKKVKGCLPPGPKPLPILGNLLQLKSREIHKPLLEFNKKYGPVYTLYMGS 77

  Fly    95 QLTVVMSDYKMIRECF--RREEFTGRPDTPFMQ-TLNGYGIINSTGKLWKDQRRFLHDKLRQFGM 156
            ...||:..|:.::|..  ..|:|:||.:.|.:. |..||||..|.|:.||:.|||....||.|||
 Frog    78 MPAVVLCGYEAVKEALVDNAEKFSGRAEVPIVNLTTQGYGIAFSNGERWKELRRFSLTTLRNFGM 142

  Fly   157 TYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRR 221
                 ||:.:::||..|:|..:...|.:.|.....:.:|..:|||||||::...||...|.|.:.
 Frog   143 -----GKRSIEERIQEEIHFLLEAFHETQGSFFSPAFIIRRSVSNVICSVVFGKRFDYTDQKLQI 202

  Fly   222 FNFLIEEGMRLFGEI--HTVDYIP-TMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPN 283
            ...||.|.:|....|  ...::|| .:...|.   ..:|:.:|.....|:.::::.:|.::.||:
 Frog   203 LLDLIAENLRRVDNIWVQVYNFIPKLLNILPG---PHHKLTENYKAQLRYVEEIVQEHGKTLDPS 264

  Fly   284 NIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVI----IDLFSAGMETIKTTLLWINVFM 344
            ..:|.:|.:|.::|:.:.          |.|.|..||.:    :|:|.||.|:..:||.:..:.:
 Frog   265 APQDYIDAFLLKMEQERK----------KAHTEYNVQNLLSCSLDIFFAGQESTSSTLGYGLLIL 319

  Fly   345 LRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNG 409
            ::.|....:||.|::.|:||.|.|.::|...:|.||:.|.|.||.....||...||.|.|....|
 Frog   320 MKYPHIKEKVQAEIESVIGRSRRPCMDDRAKMPYTEAVIHEIMRFIDFFPLGVPHSVTEDTLYRG 384

  Fly   410 YTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARM 474
            |.||.|:.:.|.::||..||:::|:|:||.|..|::.:|..||.|.|:.|..|:|.|.|..|||:
 Frog   385 YVIPKGTTIFPFLHSVLFDPSMFERPQEFYPGHFLNQDGSFRKNEGFMAFSAGKRACPGKSLARV 449

  Fly   475 ELFLFFASFMHCFDIALPEGQPLPSL 500
            |:||:..|.:..||       |.|:|
 Frog   450 EIFLYLTSILQQFD-------PQPAL 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	140/426 (33%)
MGC69353	NP_001001212.1	CYP2	67..491	CDD:410652	141/427 (33%)