Protein Alignment Cyp18a1 and Cyp12c1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 119/555 - (21%)
• Similarity: 209/555 - (37%)
• Gaps: 153/555 - (27%)

  Fly     3 ADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGP--WGLPVIGY 65
            |.||     ::||:.:.:|                      .:.:.||    |||  |
  Fly    24 ASSY-----VQQLESEWEG----------------------AKPFTEL----PGPTRW------- 50

  Fly    66 LLFMGSEKHTRFMELA---------KQYGS--LFSTRLGSQLTVVMSDYKMIRECFRRE---EFT 116
            .||.|.:|...:.:|.         ||:|.  |.....|...||...:.:...:.:|.|   ...
  Fly    51 QLFRGFQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVR 115

  Fly   117 G-----------RPDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQF-GMTYMGNGKQQMQKR 169
            |           |.|..|...:..:|    .|..|...|..::..|.|. .:.......|::.::
  Fly   116 GGAEPVIHYRNKRKDEFFKNCMGLFG----NGAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQ 176

  Fly   170 IMTEVHEFIGHLHASDGQ--PVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIE----- 227
            .:..:.|    :...:.|  |.|....|:......:.::.:.          |....|.|
  Fly   177 FVNRIRE----IRDKESQEVPGDFMNTINHLTFESVATVALD----------RELGLLREANPPP 227

  Fly   228 EGMRLFGEIHTV--------------DYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKR 278
            |..:||..|..:              .||||    |:              .::|        .|
  Fly   228 EASKLFKNIEVLMDSFFDLGVRPSLYRYIPT----PT--------------YKKF--------SR 266

  Fly   279 SFDPNNIRDLVDFYLCE-IEKAKAEGTDAELFDGKNHEEQLVQV--------IIDLFSAGMETIK 334
            :.|  .|.|....|:.: ||:...:.:..:..|.|:..|||:|:        .:|:...|::|..
  Fly   267 AMD--EIFDTCSMYVNQAIERIDRKSSQGDSNDHKSVLEQLLQIDRKLAVVMAMDMLMGGVDTTS 329

  Fly   335 TTLLWINVFMLRNPKEMRRVQDE-LDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATT 398
            |.:..|.:.:.:||::.:|:::| |.::...|...|:||::.||...:.|.||:|... |.....
  Fly   330 TAISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYP-VTFGNA 393

  Fly   399 HSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFI----DTEGKVRKPE----- 454
            .|...||.|:||.||.|:.::...:.:..|..|:.:.:||.|.|::    |.:..|...:
  Fly   394 RSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAF 458

  Fly   455 YFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDI 489
            .::|||.|.|||:|..:..:|:.|..|:.:..|.|
  Fly   459 IYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHI 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	100/462 (22%)
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	102/465 (22%)