Protein Alignment Cyp18a1 and cyp2p6

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_956433.1
• Gene: cyp2p6 / 393108
• ZFINID: ZDB-GENE-040426-790
• Length: 496
• Species: Danio rerio
• Alignment Length: 510
• Identity: 178/510 - (34%)
• Similarity: 263/510 - (51%)
• Gaps: 52/510 - (10%)

  Fly    29 VFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFSTRL 92
            |||       ||...:|| :..:..|||||.||:||.|..:...| |....:|:::|||:.|..|
Zfish    21 VFL-------LLSNYIRN-KTPKNFPPGPWPLPIIGNLYHIDFNKIHLEVEKLSEKYGSVVSVHL 77

  Fly    93 GSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTLNG-YGIINSTGKLWKDQRRFLHDKLRQF 154
            ..|.||:::.||.::|.:  :.:....||:.|.:..:.| .|::..:|..||.||||....||.|
Zfish    78 FGQRTVILNGYKQVKEVYIQQGDNVADRPELPMIHDIAGDNGLVAPSGYKWKQQRRFALSTLRNF 142

  Fly   155 GMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKF 219
            |:     ||:.::..|..|.|.....:...:|:|.|...:::.|:|||||.|:...||...|..|
Zfish   143 GL-----GKKSLEPSINLECHYLNEAISNENGRPFDPHLLLNNAISNVICVLVFGNRFDYSDHHF 202

  Fly   220 RRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIS-----------TAKNKIAQNRAEMQRFYQDVI 273
            :.....|.|.|.|.|.|....|    ..:|.|.           |..||:..       |.::.:
Zfish   203 QTLLNDINEAMYLDGTIWAQLY----NSYPRIMRLLPGPHKKNITLWNKVID-------FARERV 256

  Fly   274 DDHKRSFDPNNIRDLVDFYLCEIEKAK---AEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKT 335
            .:|:..:||:|.||.||.:|.|:||.|   |.|.|.         |.|....:|||.||.||..|
Zfish   257 KEHRVDYDPSNPRDYVDCFLAEMEKLKDDTAAGFDV---------ENLCICTLDLFVAGTETTST 312

  Fly   336 TLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHS 400
            ||.|..::|::.|:...:||:|:|:|:|..|.|::.|...:|.|.:.|.|..|..:|..|....:
Zfish   313 TLSWSLLYMIKYPEIQAKVQEEIDRVIGSSRHPSVSDRDNMPYTNAVIHEIQRFGNIAALNLPRA 377

  Fly   401 PTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRM 465
            ..:|:::..|.||.|:.||..:.||..|.:.||.|..|.|..|:|.|||.|:.:.|:||.:|:|:
Zfish   378 AVKDIQVGKYLIPKGTIVIGNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRV 442

  Fly   466 CLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520
            |||:.||||||||||.|.:..|..:.|.|.. ||....:|.|..|:.||:|...|
Zfish   443 CLGEQLARMELFLFFTSLLQHFTFSSPAGVE-PSFNYKLGTTRAPKPFKLCAVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	154/446 (35%)
cyp2p6	NP_956433.1	CYP2	69..491	CDD:410652	155/447 (35%)