Protein Alignment Cyp18a1 and Cyp4ae1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 112/541 - (20%)
• Similarity: 202/541 - (37%)
• Gaps: 103/541 - (19%)

  Fly    26 LLMVFLGLLALVTLLQWLVR-NYRELRK----LPPGPWGLPVIG----YLLFMGSEKHTRFMELA 81
            :|:|.|..|.:..|:..|.| ..:|||.    :.|....:|::|    ...|.....|.:|.|..
  Fly     1 MLVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYV 65

  Fly    82 KQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLNGY---GIINSTGKLWKDQ 143
            |::|..|...:...:.:|.::.:.|....:.:....:....|  .|.|:   |::.|.||.|...
  Fly    66 KRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYF--ALRGWLGDGLLLSRGKEWHTM 128

  Fly   144 RR-----FLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVI 203
            |:     |....|.||...:      ..|..|:.|....:.:    ..:.|::.|::.:|..::|
  Fly   129 RKIITPTFHFSILEQFVEVF------DRQSSILVERLRTLSY----GNEVVNIYPLVGLAALDII 183

  Fly   204 CSLMMSTR-----------FSIDD------PKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSI 251
            ....|...           .::.|      .:|.|.:.|.....||              |:||
  Fly   184 TETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRL--------------CWPS- 233

  Fly   252 STAKNKIAQNRAEMQRFYQDVIDDHKRSF-------DPNNIRDLVDFYLCEIEKAKAEG---TDA 306
              ...|.......:..|...:|:..:|..       .|.....|:|..|    :|..:|   ||.
  Fly   234 --GFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLL----RATVDGQPLTDK 292

  Fly   307 ELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGR--HRLPT 369
            ::.|..|          .....|.:|..:.:.:....:.|:....:::.:||....|:  .|...
  Fly   293 QIRDEVN----------TFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVI 347

  Fly   370 IEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEK 434
            :.|...||.....:.||:|....:| |......:|:.::...||.|::|:.|:..:..|..::..
  Fly   348 LSDFATLPYLSCVVKESLRLYPPIP-AVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTD 411

  Fly   435 PEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPS 499
            |..|:|.|.:..|.....|..:|||..|.|.|:|...|.:|:.......:..:       |.||
  Fly   412 PLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHY-------QLLP- 468

  Fly   500 LKGNVGATITPESFKVCLKRR 520
                :||.:.| |.|:.|:.:
  Fly   469 ----MGADVEP-SIKIVLRSK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	92/466 (20%)
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	92/466 (20%)