Protein Alignment Cyp18a1 and Cyp4d2

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 136/538 - (25%)
• Similarity: 224/538 - (41%)
• Gaps: 97/538 - (18%)

  Fly    33 LLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAK----QYGSLFSTRLG 93
            |:|..|||.|.....|....:.|||..||.:|.||........:.|:..|    :||.|:...:.
  Fly    10 LVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWIL 74

  Fly    94 SQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLN---GYGIINSTGKLWKDQRRFL----HDK- 150
            .||.|..:|.:.|......::...:.:  ..:.||   |.|::.|||:.|..:|:.:    |.|
  Fly    75 HQLAVFSTDPRDIEFVLSSQQHITKNN--LYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKI 137

  Fly   151 LRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQ-PVDMSPVISVAVSNVICSLMMSTRFSI 214
            |.||...:      ..|..:|.|..:     ..:||. |:::.|||.:...::|....|.|:.:.
  Fly   138 LEQFVEIF------DQQSAVMVEQLQ-----SRADGMTPINIFPVICLTALDIIAETAMGTKINA 191

  Fly   215 DD----PKFRRFNFLIEEGMRLFGEIHT---VDYI-----PTMQCFPSISTAKNKIAQNRA--EM 265
            ..    |..:..|.:....::.|  ||.   ||:|     ||        .||.   |::|  .|
  Fly   192 QKNPNLPYVQAVNDVTNILIKRF--IHAWQRVDWIFRLTQPT--------EAKR---QDKAIKVM 243

  Fly   266 QRFYQDVIDDHKRSFDPNNIRDL-----VDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDL 325
            ..|.:::|.:.:.:. .||.::.     |:|...:...|..:.......||....::.::..:|.
  Fly   244 HDFTENIIRERRETL-VNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDT 307

  Fly   326 FS-AGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP--TIEDLQYLPITESTILESM 387
            |. .|.:|..:.:.:....:.|:|:..:|:|.|:..|:|..|..  |:.||..|...|:.|.||:
  Fly   308 FMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESL 372

  Fly   388 RRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRK 452
            |....||:..... ..|||:.|..||||::....|..:..||..:|.|:||||.|| |.:.....
  Fly   373 RLHPPVPMIGRWF-AEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-DADVPQIH 435

  Fly   453 PEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCL 517
            |..:|||..|.|.|:|...|.:|:....:..:..|::.
  Fly   436 PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELL--------------------------- 473

  Fly   518 KRRPLGPTAADPHHMRNV 535
               ||||   :|.|..|:
  Fly   474 ---PLGP---EPRHSMNI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	111/460 (24%)
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	118/482 (24%)