Protein Alignment Cyp18a1 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 567
• Identity: 113/567 - (19%)
• Similarity: 212/567 - (37%)
• Gaps: 152/567 - (26%)

  Fly    29 VFLGLL-------ALVTLLQWLVRNYRELRKLPPGPWGLPVIGY-LLFMGSEKH---TRFMELAK 82
            :|:|||       .|:.|:.::           |||..||::|: ..|:|...|   .:..|..:
  Fly    13 LFVGLLLYHLKFKRLIDLISYM-----------PGPPVLPLVGHGHHFIGKPPHEMVKKIFEFME 66

  Fly    83 QYG--SLFSTRLGSQLTVVM---SDYKMIRECFRREEFTG--RPDTPFMQTLNGYGIINSTGKLW 140
            .|.  .:....||.:|.|:|   .|.:::....|..:..|  :...|:::.    |::.|.|:.|
  Fly    67 TYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKE----GLLVSRGRKW 127

  Fly   141 KDQRRFL----HDKLRQFGMTYMGNGKQQM-----QKRIMTEVHEFIGHLHASDGQPVDMSPVIS 196
            ..:|:.:    |.|:....:.....|.:.:     |.|:.          |...|  ..:...|:
  Fly   128 HKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLK----------HGDSG--FSLYDWIN 180

  Fly   197 VAVSNVICSLMMSTRFSID---DPKF----RRFNFLIEEGMRLFGEIHTVD--YIPTMQCFPSIS 252
            :...:.||...|....:..   |.::    :..:.::.:  |:|..::..|  |:.|     .::
  Fly   181 LCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHK--RMFNILYRFDLTYMLT-----PLA 238

  Fly   253 TAKNK------------IAQNRAEMQR-------------------------FYQDVIDDHKRSF 280
            .|:.|            |.|.|.|:.|                         ..|..:|:  |..
  Fly   239 RAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE--RPL 301

  Fly   281 DPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFML 345
            ...:||:.||.::.|                                 |.:|..:.|::....:.
  Fly   302 SNLDIREEVDTFMFE---------------------------------GHDTTSSALMFFFYNIA 333

  Fly   346 RNPKEMRRVQDELDQVVGRHRLPTI--EDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELN 408
            .:|:..::..:|:..|||..:...:  |.|..|...:..:.|::|....||| .......|.|:|
  Fly   334 THPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPL-LGRKVLEDCEIN 397

  Fly   409 GYTIPAGSH--VIPLINSVHMDPNLWEKPEEFRPSRF-IDTEGKVRKPEYFIPFGVGRRMCLGDV 470
            |..||||::  :.||.  :.....|:.:|..|:|.|| :.|..:...|..:|||..|.|.|:|..
  Fly   398 GKLIPAGTNIGISPLY--LGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQK 460

  Fly   471 LARMELFLFFASFMHCFDIAL--PEGQPLPSLKGNVGATITPESFKV 515
            .|.:|:....|:.:..:::..  ...:|...:...:..|..|..|||
  Fly   461 FAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	94/498 (19%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	93/491 (19%)