Protein Alignment Cyp18a1 and Cyp2u1

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001380742.1
• Gene: Cyp2u1 / 310848
• RGDID: 1309433
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 197/538 - (36%)
• Similarity: 293/538 - (54%)
• Gaps: 43/538 - (7%)

  Fly    12 LRQLQVQQDGDAQHLLMV--FLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVI---GYLL---- 67
            ||....:|.|...||..|  .|.|..|..||.|:....:....:||||...|::   ||||
  Rat     7 LRPAAGEQPGVGPHLQAVGGALLLCGLAVLLDWVWLQRQRAGGIPPGPKPRPLVGNFGYLLLPRF 71

  Fly    68 -----FMGS-------EKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGR 118
                 ::||       .:|.....||:.||::||..:|.:|.||:||::.:||..  :.|.|:.|
  Rat    72 LRLHFWLGSGSQTDTVGRHVYLARLARVYGNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDR 136

  Fly   119 PDTPFMQTL-NGYGIINS-TGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHL 181
            |..|.:..| ...||:.: .|.:||.||||.|..||.||:     ||..::.||:.|.......:
  Rat   137 PRMPLISILTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGL-----GKLSLEPRIIEEFAYVKAEM 196

  Fly   182 HASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMR--LFGEIHTVDYIPT 244
            ......|....||||.||||:||||....||...:.:|::....:..|:.  |..::..::..|.
  Rat   197 QKHGEAPFSPFPVISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLCPW 261

  Fly   245 MQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYL--CEIEKAKAEGTDAE 307
            ....| ....| ::.|...::..|.:::|.:|:.|.|.||.:|.:|.||  .:.||.|.:||:
  Rat   262 FYYLP-FGPFK-ELRQIERDITCFLKNIIKEHQESLDANNPQDFIDMYLLHTQEEKDKCKGTN-- 322

  Fly   308 LFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIED 372
             ||    |:.|..:|.|||.||.:|...:|||..::|..||...::|.:|:::|:||.|.|::.|
  Rat   323 -FD----EDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQKKVHEEIERVIGRDRAPSLTD 382

  Fly   373 LQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEE 437
            ...:|.||:||:|..|.|.:||||..|..:....|.||:||.|:.|:|.:.|:|.||.:||||::
  Rat   383 KAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKPDD 447

  Fly   438 FRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKG 502
            |.|.||:|.:|::.|.|.|||||:|:|:|:|:.||:|||||.|.|.|..|..|||||...|.:.|
  Rat   448 FCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFALPEGSEKPIMTG 512

  Fly   503 NVGATITPESFKVCLKRR 520
            ..|.|:.|..|.|.:.:|
  Rat   513 RFGLTLAPHPFNVTVSKR 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	183/489 (37%)
Cyp2u1	NP_001380742.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	304	1.000	Domainoid score	I1330
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H77704
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2426
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm45879
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	1	1.100	-	-	O	PTHR24300
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.970