Protein Alignment Cyp18a1 and Cyp2c7

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_058854.1
• Gene: Cyp2c7 / 29298
• RGDID: 620379
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 168/507 - (33%)
• Similarity: 267/507 - (52%)
• Gaps: 40/507 - (7%)

  Fly    27 LMVF--LGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG----SEKHTRFMELAKQYG 85
            |:.|  |.|.:|:.|..|  |.....|||||||..||:||..|.:.    |:..|:|   :|.||
  Rat     3 LVTFLVLTLSSLILLSLW--RQSSRRRKLPPGPTPLPIIGNFLQIDVKNISQSLTKF---SKTYG 62

  Fly    86 SLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFL 147
            .:|:..||||.||::..|:.|:|..  ..|:|:||...|..:.: .|:||:.|.|..||:.|||.
  Rat    63 PVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVTKGFGIVFSNGNRWKEMRRFT 127

  Fly   148 HDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRF 212
            ....|..|:     ||:.::.|:..|....:..|..:.|.|.|.|.:::.|..|||||:.....|
  Rat   128 IMNFRNLGI-----GKRNIEDRVQEEAQCLVEELRKTKGSPCDPSLILNCAPCNVICSITFQNHF 187

  Fly   213 SIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQ-C--FPSI----STAKNKIAQNRAEMQRFYQ 270
            ...|.:...|...:.|.:::...       |.|| |  |||:    ....:|||:|...|:.:..
  Rat   188 DYKDKEMLTFMEKVNENLKIMSS-------PWMQVCNSFPSLIDYFPGTHHKIAKNINYMKSYLL 245

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKT 335
            ..|::|:.|.|..|.||.||:||  |::.:|...:...:.    .|.|...|:||..||.||:.|
  Rat   246 KKIEEHQESLDVTNPRDFVDYYL--IKQKQANNIEQSEYS----HENLTCSIMDLIGAGTETMST 304

  Fly   336 TLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHS 400
            ||.:..:.:::.|....:||:|:|:|:||||.|.::|.:::|.|::.|.|..|..:.||....|:
  Rat   305 TLRYALLLLMKYPHVTAKVQEEIDRVIGRHRSPCMQDRKHMPYTDAMIHEVQRFINFVPTNLPHA 369

  Fly   401 PTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRM 465
            .|.|::...|.||.|:.|:..:.||..|...:..||.|.|..|:|..|..:|.:||:||..|:|.
  Rat   370 VTCDIKFRNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFLPFSAGKRA 434

  Fly   466 CLGDVLARMELFLFFASFMHCFDI-ALPEGQPLPSLKGNVGATITPESFKVC 516
            |:|:.||||:||||..:.:..|:: :|...:.:.::....|....|.::::|
  Rat   435 CVGEGLARMQLFLFLTTILQNFNLKSLVHPKDIDTMPVLNGFASLPPTYQLC 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	142/440 (32%)
Cyp2c7	NP_058854.1	CYP2C-like	61..485	CDD:410758	143/441 (32%)