Protein Alignment Cyp18a1 and Cyp2w1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001414598.1
• Gene: Cyp2w1 / 288517
• RGDID: 1305193
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 156/492 - (31%)
• Similarity: 242/492 - (49%)
• Gaps: 54/492 - (10%)

  Fly    33 LLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR-FMELAKQYGSLFSTRLGSQL 96
            ||.|..||:...::....|:.||||..||.:|.|..:|.....| .|||:::||.:|:..||||.
  Rat    14 LLGLWGLLRGCAQDPSMTRQWPPGPRPLPFLGNLHLLGVTHQDRALMELSERYGPMFTIHLGSQK 78

  Fly    97 TVVMSDYKMIRECF--RREEFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTY 158
            |||:|.|:::||..  ...|...||..|..|.: .|.||..|:|..||..|:|....|:..|:.
  Rat    79 TVVLSGYEVVREALVGTGHELADRPPIPIFQLIQRGGGIFFSSGVHWKVARQFTVRTLQSLGIR- 142

  Fly   159 MGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFN 223
                :..|..:::.|:....|.|.:..|||..:: ::..|..|:..:|:...||...||.|....
  Rat   143 ----QPPMVGKVLQELVCLKGQLDSYGGQPFPLT-LLGWAPCNITFTLLFGQRFDYQDPVFVSLL 202

  Fly   224 FLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNR------AEMQRFYQDVIDDHKRSFDP 282
            .||::.|.|.|.       |.:|.|.:.......:..:|      .|::...:.:::..:... |
  Rat   203 SLIDQVMVLLGS-------PGIQLFNTFPRLGALLRLHRPVLSKIEEVRTILRTLLEAQRPPL-P 259

  Fly   283 NN--IRDLVDFYLCEIEKAKAEGTD--AELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVF 343
            |.  .|..|:..|       .:|.|  .::|.    |..::...:|:..||.||...||.|....
  Rat   260 NGSPARSYVEALL-------QQGQDDPEDMFS----EANVLACTLDMVMAGTETTAATLQWAVFL 313

  Fly   344 MLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSP---TRDV 405
            |:::|....|||:|||:|:|..:||..||.:.||.|.:.:.|..|..:::|    |.|   ..|:
  Rat   314 MVKHPHVQGRVQEELDRVLGPGQLPQPEDQRALPYTSAVLHEVQRYITLLP----HVPRCTAADI 374

  Fly   406 ELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDV 470
            :|.||.:|.|:.||||:.||.:|...||.|.:|.|:.|:|.:|...|...|:||..|||:|:|:.
  Rat   375 QLGGYLLPKGTPVIPLLTSVLLDKTQWETPSQFNPNHFLDAKGCFMKRGAFLPFSTGRRVCVGES 439

  Fly   471 LARMELFLFFASFMHCFDIALPEG--------QPLPS 499
            |||.||||.||..:..:.:..|.|        :|.|:
  Rat   440 LARTELFLLFAGLLQQYHLLPPPGLSPADLDLRPAPA 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	136/439 (31%)
Cyp2w1	NP_001414598.1	None