Protein Alignment Cyp18a1 and Cyp2g1

DIOPT Version :10

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_036919.1
• Gene: Cyp2g1 / 25251
• RGDID: 2477
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 170/516 - (32%)
• Similarity: 280/516 - (54%)
• Gaps: 41/516 - (7%)

  Fly    21 GDAQHLLMVFLGLLALVTLLQWLVRNYRELR--KLPPGPWGLPVIGYLLFMGSE-KHTRFMELAK 82
            |.|..:.|. |.|..|:.|:.|    .|..|  ||||||..:|.:|.||.:..: ....|::|.|
  Rat     4 GGAFSIFMT-LCLSCLLILIAW----KRTSRGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQK 63

  Fly    83 QYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQ-TLNGYGIINSTGKLWKDQR 144
            :|||:|:...|.:..|::..::.::|..  :.::|:||.:.|.:: ...|||:..|.|:.||..|
  Rat    64 KYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILR 128

  Fly   145 RFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMS 209
            ||....||.|||     ||:.:::||..|....:..||...|.|:|.:..:|..|||||||::..
  Rat   129 RFSLTVLRNFGM-----GKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFG 188

  Fly   210 TRFSIDDPKFRRFNFLIEEG---MRL-FGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQ 270
            .||..:|.:||....:|.|.   |.: :.:::.: |...:|.||.   ..|::.....|::.|..
  Rat   189 KRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDM-YWGVIQYFPG---RHNRLYNLIEELKDFIA 249

  Fly   271 DVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKT 335
            ..:..::.||||:|.||.:|.:|.::.:.|::....  |:.||    ||...::||.||.||:.:
  Rat   250 SRVKINEASFDPSNPRDFIDCFLIKMYQDKSDPHSE--FNLKN----LVLTTLNLFFAGTETVSS 308

  Fly   336 TLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHS 400
            ||.:..:.:::.|:...::.:|::||:|.||.|.::|...:|.|::.|.|..|.:.||||...|:
  Rat   309 TLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHN 373

  Fly   401 PTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRM 465
            ..||....||.:|.|:.|.|||.||..||..:..||.|.|..|:|.:|:.:|.:.|:.|..|:|:
  Rat   374 VIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRI 438

  Fly   466 CLGDVLARMELFLFFASFMHCFDI--ALPEGQPLPSLK----GNVGATITPESFKVCLKRR 520
            |:|:.||||||||:|.|.:..|.:  .:|......:.|    ||:     |.::::|...|
  Rat   439 CVGEALARMELFLYFTSILQRFSLRSLVPPADIDIAHKISGFGNI-----PPTYELCFMAR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	144/442 (33%)
Cyp2g1	NP_036919.1	CYP2G	65..489	CDD:410763	145/443 (33%)