Protein Alignment Cyp18a1 and Cyp2b1

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_038950984.1
• Gene: Cyp2b1 / 24300
• RGDID: 2466
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 167/532 - (31%)
• Similarity: 271/532 - (50%)
• Gaps: 59/532 - (11%)

  Fly    29 VFLGLLALVTLLQWLVRNYRELR-KLPPGPWGLPVIGYLL----------FM--GSEKHTRF--- 77
            :.|.|..||..|..|||.:.:.| ..||||..||::|.||          ||  |..:.|..
  Rat     5 ILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQPGPPQPTDLQGV 69

  Fly    78 ------------MELAKQYGSLFSTRLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFMQTL- 127
                        ::|.::||.:|:..||.:..|::.....|:|..  :.|:|:||.....::.:
  Rat    70 VVASTMQHLSPAVKLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIF 134

  Fly   128 NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMS 192
            ..||:|.:.|:.||..|||....:|.|||     ||:.:::||..|....:..|..|.|.|:|.:
  Rat   135 KEYGVIFANGERWKALRRFSLATMRDFGM-----GKRSVEERIQEEAQCLVEELRKSQGAPLDPT 194

  Fly   193 PVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVD------YIPTMQCFPSI 251
            .:.....:|:|||::...||...|.:|.|   |:|...|.|..:.:..      :...::.||.
  Rat   195 FLFQCITANIICSIVFGERFDYTDRQFLR---LLELFYRTFSLLSSFSSQVFEFFSGFLKYFPG- 255

  Fly   252 STAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEE 316
              |..:|::|..|:..:...:::.|:.:.||:..||.:|.||..:||.|:  ....:|    |.|
  Rat   256 --AHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKS--NHHTVF----HHE 312

  Fly   317 QLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITES 381
            .|:..::.||.||.||..|||.:..:.||:.|....:||.|:|||:|.|||||::|...:|.|::
  Rat   313 NLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDA 377

  Fly   382 TILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDT 446
            .|.|..|.|.:||:...|..|:|....||.:|..:.|.|:::|...||..::.|:.|.|..|:|.
  Rat   378 VIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDA 442

  Fly   447 EGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA---LPEGQPLPSLKGNVGATI 508
            .|.::|.|.|:||..|:|:|||:.:||.||||||.:.:..|.::   .|:...|...:..:|.
  Rat   443 NGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGK-- 505

  Fly   509 TPESFKVCLKRR 520
            .|.::::|...|
  Rat   506 IPPTYQICFSAR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	156/501 (31%)
Cyp2b1	XP_038950984.1	CYP2B	88..512	CDD:410765	142/442 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820