Protein Alignment Cyp18a1 and Cyp2j13

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_663523.2
• Gene: Cyp2j13 / 230459
• MGIID: 2385197
• Length: 503
• Species: Mus musculus
• Alignment Length: 503
• Identity: 165/503 - (32%)
• Similarity: 264/503 - (52%)
• Gaps: 30/503 - (5%)

  Fly    23 AQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG-SEKHTRFMELAKQYGS 86
            |.||..:.|..:..:.|..:|  ..|..:..||.|..||.:|....|. ::.|....:..|:||:
Mouse    15 ALHLRTLLLAAVTFLFLADYL--KSRRPKNYPPRPPRLPFVGNSFQMDLTQSHLAVQKFVKKYGN 77

  Fly    87 LFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFM-QTLNGYGIINSTGKLWKDQRRFLH 148
            :.|...|.:..|::|...:|:|.|..  |.|..|...|.. |..||.|:|.|:|:.||:||||..
Mouse    78 VISLDFGIKSAVIISSLPLIKEAFSHLDENFINRRIFPLQRQIFNGNGLIFSSGQTWKEQRRFAL 142

  Fly   149 DKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFS 213
            ..||.||:     ||:.::.||..|....:..:...:|||.|....|..||||:|||:....||.
Mouse   143 MTLRNFGL-----GKKSLEHRIQEEASHLVEAIGEEEGQPFDPHFKIYSAVSNIICSITFGERFE 202

  Fly   214 IDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRA------EMQRFYQDV 272
            ..|.:|:....|:::.|.| |....:.::  ...||.|:  |:...|::.      :::.:..|:
Mouse   203 YHDSQFQELLQLLDKAMYL-GTTSLMVHL--YNIFPWIT--KHLPGQHQTLLATWRKLKSYIADI 262

  Fly   273 IDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTL 337
            ||:|::.::|:..||.:|.:|.|:  ||..|.....|    :||.|:...:|||.||.||..:||
Mouse   263 IDNHRKDWNPDEPRDFIDAFLNEM--AKYPGKTTTSF----NEENLICSTLDLFLAGTETTSSTL 321

  Fly   338 LWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPT 402
            .|..::|...|:....||.|:|:|:|:.:.|::.|...:|.|.:.:.|.:|..:.|||.......
Mouse   322 RWALLYMALYPEVQENVQAEIDRVIGQSKHPSLADRDSMPYTNAVVHEILRMGNSVPLNIPREVA 386

  Fly   403 RDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCL 467
            .|..|.|:.:|..|.|:..:.::||||..|..|:.|.|..|:: .|:.:|.|.|:||.:|:|.||
Mouse   387 VDTTLAGFHLPKRSVVMTNLTALHMDPKEWATPDIFNPEHFLE-NGQFKKRESFLPFSMGKRACL 450

  Fly   468 GDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKV 515
            |:.|||.|||:||.:.:..|....|..:.| |||..:|.||:|.|:::
Mouse   451 GEQLARSELFIFFTALVQKFTFKPPANENL-SLKFRLGITISPVSYRI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	158/472 (33%)
Cyp2j13	NP_663523.2	p450	44..475	CDD:278495	148/447 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	290	1.000	Domainoid score	I1539
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm43796
orthoMCL	1	0.900	-	-		OOG6_100036
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.720