Protein Alignment Cyp18a1 and Cyp2c70

DIOPT Version :9

• Sequence 1: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_663474.2
• Gene: Cyp2c70 / 226105
• MGIID: 2385878
• Length: 489
• Species: Mus musculus
• Alignment Length: 503
• Identity: 159/503 - (31%)
• Similarity: 266/503 - (52%)
• Gaps: 33/503 - (6%)

  Fly    27 LMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFM-ELAKQYGSLFST 90
            |.:|||:.....|..:|...:|...||||||..||::|.:|.:..:..::.| .|||:||.:|:.
Mouse     3 LFIFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKSMGMLAKKYGPVFTV 67

  Fly    91 RLGSQLTVVMSDYKMIRECF--RREEFTGRPDTPFM-QTLNGYGIINSTGKLWKDQRRFLHDKLR 152
            .||.:.|||:..||.::|..  :.:||:.:.|:..: :|..|.||:.|.|:.||..|||....||
Mouse    68 YLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGIVFSNGETWKQTRRFSLMVLR 132

  Fly   153 QFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDP 217
            ..||     ||:.::.||..|:...:..|..::|.|.|.|.:::....|||.:::...||..:|.
Mouse   133 SMGM-----GKKTIEDRIQEEILYMLDALRKTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQ 192

  Fly   218 KFRRF--NF------LIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVID 274
            .|:.|  ||      |.....:|......:.|:|.:.         |:..::..:.::|..:.|:
Mouse   193 TFQDFMENFHRKIEILASPWSQLCSAYPILYYLPGIH---------NRFLKDVTQQKKFILEEIN 248

  Fly   275 DHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLW 339
            .|::|.|.:|.:|.:|::|.::||.|.........|      .||..|.|||.||.||..:|:.:
Mouse   249 RHQKSLDLSNPQDFIDYFLIKMEKEKHNQKSEFTMD------NLVVSIGDLFGAGTETTSSTVKY 307

  Fly   340 INVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRD 404
            ..:.:|:.|:...::|:|:..|:||||.||::|..::|.|::.:.|..|....||:.:....|:|
Mouse   308 GLLLLLKYPEVTAKIQEEIAHVIGRHRRPTMQDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQD 372

  Fly   405 VELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGD 469
            ||..||.||.|:.|:..:.||..|...:..||:|.|..|:|.:|..:|.:||:.|..|||.|:|:
Mouse   373 VEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKKSDYFVAFSAGRRACIGE 437

  Fly   470 VLARMELFLFFASFMHCFDI-ALPEGQPLPSLKGNVGATITPESFKVC 516
            .|||||:||...:.:..|.: .|.:.:.:.:.....|....|..|::|
Mouse   438 GLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVPPPFELC 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp18a1	NP_523403.2	p450	54..517	CDD:278495	150/476 (32%)
Cyp2c70	NP_663474.2	p450	30..486	CDD:278495	150/476 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC78
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	1	1.000	-	-		otm43796
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820